Hormonal Risk Factors May Predict Alzheimer Endophenotype
Cognitively normal women have increased AD endophenotype, with higher β-amyloid deposition, lower glucose metabolism, and lower gray and white matter volumes.
Alzheimer Disease and Dementia
Breakthrough Therapy Designation Granted to Novel Therapy for Alzheimer Disease Agitation
The FDA has granted Breakthrough Therapy designation to AXS-05 (Axsome Therapeutics) for the treatment of Alzheimer disease agitation.
FDA Approves DBS Neurostimulation System With Brain Signal Tracking
The FDA has approved the Percept™ PC Deep Brain Stimulation (DBS) system (Medtronic) with BrainSense™ technology for neurological disorders.
Pimavanserin sNDA Submitted for Dementia-Related Psychosis
Acadia Pharmaceuticals has submitted a supplemental New Drug Application to the FDA for pimavanserin for the treatment of hallucinations and delusions associated with dementia-related psychosis.
Antiepileptic Drugs May Increase Death Risk in Alzheimer Disease
Mortality risk is highest during the first three months of treatment with antiepileptic drugs.
Assessing Diagnostic Accuracy of Alzheimer Disease, Dementia by Primary Care Providers
Researchers sought to identify health care system factors that contribute to missed or delayed diagnosis of dementia by primary care providers.
First Diagnostic Agent Approved to Image Tau Pathology for Alzheimer Disease
The FDA has approved Tauvid for PET imaging of the brain to estimate the density and distribution of aggregated tau neurofibrillary tangles.
Anti-TNF Agents May Lower Alzheimer Disease Risk for Patients With Psoriasis, Rheumatoid Arthritis
A subset of patients at risk for Alzheimer disease because of systemic inflammation may benefit from receiving a tumor necrosis factor blocking agent.
Psoriasis Linked to Inreased Risk for Alzheimer Disease
The risk for AD among patients with psoriasis was significantly increased in psoriasis patients not receiving systemic therapy compared with those receiving systemic therapy.
Reviews Assess Tools to Identify, Diagnose, Treat Alzheimer Dementia
Many cognitive tests can differentiate clinical Alzheimer-type dementia from normal cognition.
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