Longitudinal Cerebrospinal Fluid Biomarker Trajectories in Alzheimer’s Disease
Total tau and phosphorylated tau follow a different pattern of change in Alzheimer’s disease.
Alzheimer Disease and Dementia
Poll: Many Adults Worried About Developing Dementia
Many adults are worried about developing dementia and about half report taking steps to maintain or improve memory.
Free Water and White Matter Hyperintensity May Predict Dementia Severity
Investigators sought to determine whether high levels of free water and white matter hyperintensity are associated with higher dementia severity and accelerated declines in episodic memory and executive function in older persons.
Gout Not Causally Associated With Alzheimer Disease
No causal association was demonstrated between gout and Alzheimer disease.
Amyloid PET Scan Associated With Changes in MCI and Dementia Clinical Management
Among Medicare beneficiaries with mild cognitive impairment or dementia of uncertain etiology, the use of amyloid PET was associated with changes in clinical management within 90 days.
Memantine/Cholinesterase Inhibitor Therapy Beneficial in Alzheimer Disease
Researchers sought to determine whether combining memantine with a cholinesterase inhibitor produced early and consistent improvements in cognition for patients with moderate to severe Alzheimer disease.
Varying Amyloid-β Levels Affect Attitudes Toward Physician-Assisted Death
Attitudes about physician-assisted death vary among patients with Alzheimer disease.
Suvorexant Evaluated for Insomnia in Patients With Alzheimer Disease Dementia
A study evaluating the safety and efficacy of suvorexant for the treatment of insomnia in patients with mild to moderate Alzheimer disease dementia was presented at AAN 2019.
Low-Dose Naproxen Does Not Reduce Progress of Presymptomatic Alzheimer Disease
Low-dose naproxen increases frequency of adverse health effects and does not reduce progression of presymptomatic Alzheimer disease in cognitively intact persons at risk.
Low Scam Awareness May Indicate Alzheimer Disease Risk in Seniors
Low scam awareness is associated with an increased risk for Alzheimer disease and mild cognitive impairment among older adults.
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