P-tau181 Biomarker Predicts Risk of Alzheimer Dementia
The presence of P-tau181 may aid in the diagnosis and identification of prognostic outcomes in Alzheimer disease.
Alzheimer Disease and Dementia
Brain Amyloid Deposition and Intracranial Atherosclerotic Disease in Adults
There is no evidence for an association between cerebral β-amyloid deposition, a marker of Alzheimer disease, and intracranial atherosclerotic plaque or stenosis.
Higher Flavonol Intake May Protect Against Alzheimer Disease
Higher flavonol intake through food sources, mostly fruits and vegetables, may protect against the development of Alzheimer disease.
Investigational Therapies Miss Primary End Point in Autosomal Dominant Alzheimer Disease Trial
Topline data were announced from the phase 2/3 DIAN-TU study of solanezumab (Eli Lilly) and gantenerumab (Genentech) in patients at risk for or with dominantly inherited Alzheimer disease.
Psychotropic Prescribing Trends Differ By Race Among Patients With Dementia
Compared with their peers, Asian patients with dementia were less likely to be prescribed antidementia drugs, and they received these drugs for fewer days per year.
High Variability in GGT Level May Predict Risk for Dementia in Patients With Diabetes
Higher gamma-glutamyltransferase variability was found to be significantly associated with increased risk for dementia among patients with diabetes.
Suvorexant Labeling Updated to Include Data on Insomnia in Alzheimer Disease
The Food and Drug Administration (FDA) has approved updates to the prescribing information for Belsomra® (suvorexant; Merck) to include study findings for the treatment of insomnia in patients with mild to moderate Alzheimer disease.
Road Proximity Linked to Incidence of Neurologic Diseases
Road proximity is associated with an increased incidence of specific neurologic disorders.
FDA to Review Donepezil Transdermal System for Alzheimer Disease
A PDUFA target date of June 30, 2020 has been assigned to the application.
Predicting Amyloid Accumulation in Patients With Objective Subtle Cognitive Difficulties
The presence of objective subtle cognitive difficulties (Obj-SCD) on neuropsychological measures may predict faster amyloid accumulation and neurogenerative changes.
Next post in Neurodegenerative Diseases
