Persistent Midlife Loneliness May Up Later Dementia, AD Risk
Persistent loneliness in midlife is an independent risk factor for later dementia and Alzheimer disease.
Alzheimer Disease and Dementia
FDA Rejects Pimavanserin sNDA for Dementia-Related Psychosis
The sNDA submission was supported by data from the pivotal phase 3 HARMONY study.
African Americans More Likely to Carry Genetic Variants Associated With Dementia
Study researchers sought to assess the racial differences in triggering receptor expressed on myeloid cells 2 in patients with Alzheimer disease.
Dementia Diagnoses Higher Among Older US Adults with Schizophrenia
The researchers sought to estimate the age-specific incidence and prevalence of dementia diagnoses among older adults with schizophrenia in the United States compared to those without serious mental illness.
Nondrug Interventions Can Help Alleviate Depression in Dementia Patients
For people with dementia with symptoms of depression, without a MDD, nondrug interventions are more efficacious than drug interventions.
Donanemab Studied in Early Symptomatic Alzheimer Disease
Donanemab, which targets a modified form of deposited amyloid-ß, results in slightly less cognitive and functional decline than placebo.
Head Injury Linked to Long-Term Risk for Dementia
The associations of head injury with dementia were examined during a median 25 years of follow-up.
Increased White Matter Hyperintensity in Alzheimer Disease and Behavioral-Variant Frontotemporal Dementia
Investigators assessed white matter hypeintensity burden in patients with Alzheimer disease and behavioral-variant frontotemporal dementia.
CNS-Active Polypharmacy Examined in Seniors With Dementia
A total of 13.9 percent of community-dwelling older adults with dementia meet the criterion for CNS-active polypharmacy.
Dexmedetomidine Oral Film Gets Breakthrough Tx Status for Acute Agitation With Dementia
BXCL501 is an oral thin film formulation of dexmedetomidine, a selective alpha-2a receptor agonist.
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