The most common adverse event in participants with early Alzheimer disease receiving high-dose aducanumab in the two phase 3 randomized clinical trials was amyloid-related imaging abnormalities-edema (ARIA-E), which occurred in 35.2% of participants.
People older than 50 years with HIV are more likely to have dementia than people without HIV.
Researchers sought to examine associations between women’s reproductive history indicators, including estrogen exposure, and brain MRI biomarkers of Alzheimer disease in midlife.
Researchers sought to explore the associations between a pro-inflammatory diet and the risk for dementia using a population-based, biomarker-validated diet inflammatory index.
The researchers sought to explore the association between cognitive reserve indicator with global cognitive function, episodic memory, and working memory over time, and explore the role of brain pathologies in such associations.
Increased coffee consumption is associated with slower cognitive decline and a lower likelihood of transitioning to mild cognitive impairment or AD status.
A pro-inflammatory diet is associated with an increased risk for incident dementia, according to a study published online.
Ethical considerations for the use of aducanumab for Alzheimer disease are addressed following the recent U.S. FDA approval of the drug.
The first human clinical trial of a nasal vaccine to slow the progression of Alzheimer disease is set to begin after nearly 20 years of research.
The link between head injury and dementia risk is not straightforward, but a neurologist and neuropsychologist discuss potential mechanisms and prevention efforts that can help increase awareness and minimize cognitive problems.
