TP73 Gene Variants Tied to Risk for Sporadic Amyotrophic Lateral Sclerosis
Researchers used sequencing data to evaluate the pathogenicity of TP73 variations in amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Exservan Now Available for Amyotrophic Lateral Sclerosis
According to the CDC, more than a thousand cases of myocarditis and pericarditis following mRNA COVID-19 vaccination have been reported to the Vaccine Adverse Event Reporting System since April 2021.
Heterogeneous Movement Disorders in Patients With C9orf72 Hexanucleotide Expansions
In this retrospective review, study researchers sought to assess the presentation of movement disorders in carriers of C9orf72 hexanucleotide repeat expansions.
Trehalose Designated Orphan Drug for ALS
SLS-005 contains the active ingredient trehalose, a low molecular weight disaccharide that crosses the blood brain barrier, stabilizes proteins and activates autophagy.
FDA Grants Fast Track Status to Arimoclomol for ALS
The FDA has granted Fast Track designation to arimoclomol (Orphazyme A/S) for the treatment of amyotrophic lateral sclerosis.
Insights Into the Diagnosis and Management of Amyotrophic Lateral Sclerosis
A diagnosis of amyotrophic lateral sclerosis can be overlooked by clinicians unfamiliar with the various signs of the disease.
FDA Grants Orphan Designation to Reldesemtiv for ALS
The FDA has granted Orphan Drug designation to reldesemtiv (Cytokinetics) for the treatment of amyotrophic lateral sclerosis.
ALS Treatment Approved for Use Via Percutaneous Endoscopic Gastrostomy Tube
The FDA has approved the supplemental New Drug Application for riluzole oral suspension to include administration via percutaneous endoscopic gastrostomy (PEG) tubes for the treatment of ALS.
Study Investigating Acthar Gel in the Treatment of ALS Discontinued
Mallinckrodt has permanently discontinued the phase 2b PENNANT trial investigating Acthar Gel (repository corticotrophin) for the treatment of amyotrophic lateral sclerosis.
AAN: Professional Soccer Players Show Increased Risk for ALS
Professional soccer players may have an increased risk for amyotrophic lateral sclerosis.
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