Immunotherapy Promising for Slowing Progression of ALS
A new immunotherapy appears to be well tolerated and possibly of benefit in patients with amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Linear Link for Physical Activity, Amyotrophic Lateral Sclerosis
There is a linear correlation for physical activity with amyotrophic lateral sclerosis.
MAPT H1 Haplotype Implicated in ALS Risk, With Genetic Overlap Between ALS and FTD
Investigators sought to identify genetic factors that may contribute to the risk for neurodegenerative diseases, such as amyotrophic lateral sclerosis and frontotemporal dementia.
Sensory Cortex Hyperexcitability Predicts Shorter Survival in ALS
Investigators assessed patients with sporadic ALS to determine the relationship between somatosensory cortex excitability and survival prognosis.
Occupational Exposure to Diesel Exhaust Tied to ALS Risk
Researchers found that for men with any occupational exposure to diesel exhaust, the odds ratio for amyotrophic lateral sclerosis increased with increasing lag periods.
Pseudobulbar Affect Linked to Mood Symptoms in Parkinsonian Syndromes
Pseudobulbar affect is characterized by episodes of inappropriate laughing or crying, and may be associated with increased anxiety and depression, as well as lower mental health status.
Riluzole Prolongs Survival in Late-Stage Amyotrophic Lateral Sclerosis
Patients who received 100 mg/day riluzole spent significantly more time in stage 4 than patients who were randomly assigned to placebo.
Evidence of Impaired Glucose Signaling in Amyotrophic Lateral Sclerosis
Further research is warranted to clarify the role played by insulin resistance in the pathogenesis of amyotrophic lateral sclerosis.
Prevalence of ALS Remains Steady in US
The prevalence of ALS in the United States has been steady.
Arimoclomol Shows Promise for Treating Rapidly Progressive SOD1 ALS
Due to the rarity of rapidly progressive SOD1 ALS, this study had a small sample size and may be limited in power.
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