Outcomes Poor Years After Radiation for Pediatric Glioma Survivors
Survivors of childhood low-grade gliomas treated with radiotherapy have poorer neuropsychological and socioeconomic-status outcomes.
Brain Cancer
Phase 3 Study of Investigative Glioblastoma Treatment Halted
AbbVie has halted enrollment in all ongoing studies of depatuxizumab mafodotin, after an Independent Data Monitoring Committee (IDMC) recommended a phase 3 study of the treatment be stopped due to a lack of survival benefit.
Lifetime Risk for Brain Metastasis Increased in Elderly With Some Common Cancers
Highest incidence seen for patients with non-small cell lung cancer and triple-negative breast cancer
Cognitive Impairment Not Common Post-Skull Radiation
Most patients undergoing skull base irradiation for cancer do not have detectable cognitive impairment.
Postoperative Stereotactic Radiosurgery Reduces Recurrence After Metastases Resection
The use of postoperative stereotactic radiosurgery could be a substitute for whole-brain radiotherapy, which has been linked to cognitive adverse effects.
Brain Tumor Histology and Incidence in Adolescents and Young Adults
Over 10 000 brain and CNS tumors are diagnosed in adolescent and young adults each year.
Electromagnetic Field Therapy Promising for Glioblastoma Treatment
Two years post-enrollment, 43% of patients in the combination therapy group were alive.
Anthracycline-Based Chemo Affects Cognition, Brain Connectivity
Anthracycline-based chemotherapy was associated with worse cognitive outcomes than nonanthracycline chemo.
VIDEO: Global Coalition to Design Adaptive Clinical Trial for Glioblastoma
The adaptive trial design will allow GBM patients to benefit from precision medicine.
DNA From Cerebrospinal Fluid May Effectively Monitor Brain Metastases
Researchers found that brain tumor mutations could be detected from ctDNA in cerebrospinal fluid.
