Effect of Pain on Functioning in Serious Mental Illness
Authors of a paper share their perspectives on the topic of chronic pain in individuals with mental health disorders.
Depression
Spravato Approved for MDD With Acute Suicidal Ideation or Behavior
The approval was based on the ASPIRE I and II trials that compared the efficacy and safety of esketamine, an N-methyl-D-aspartate receptor antagonist, to placebo in 449 adults with moderate to severe MDD who had active suicidal ideation and intent.
Botox Injections May Ease Depression
Botox injections, which are commonly used to lessen wrinkles, migraines, muscle spasms, excessive sweating, and incontinence, may also help treat depression.
Gaps Identified in Postpartum Depression Screening
Researchers explored provider screening practices in primary care, women’s health, and well-child clinics to determine if barriers exist in meeting postpartum depression screening guidelines.
Discontinuation of Anti-TNF Agents More Likely in Patients With IBD Plus Anxiety, Mood Disorders
A team of investigators assessed the impact of anxiety and mood disorders on treatment with anti-tumor necrosis factor agents in individuals with inflammatory bowel disease.
Depression, Anxiety May Be Signs That COVID-19 Is Attacking Brain
Depression and anxiety exhibited in coronavirus disease 2019 patients may be a sign that the virus impacts the central nervous system.
Polygenic Risk Scores Predict Progression to Other Disorders in Unipolar Depression
Polygenic risk scores predict the progression from unipolar depression to bipolar or psychiatric disorders.
Aspirin Does Not Prevent Late Life Depression, Despite Link to Inflammation
Depression has been linked to elevated markers of inflammation, and aspirin, a nonsteroid, anti-inflammatory medication, can irreversibly inhibit cyclooxygenase-1 and 2.
Higher Relapse Risk For Depression Between Childhood and Adolescence
Children who receive a depression diagnosis in their primary school age have a substantially higher risk of a depression relapse during adolescence compared with children who did not receive a depression diagnosis during their primary school age.
Replicating Neuroimaging Abnormalities in Major Depression
Convergent abnormalities were observed in secondary analyses across portions of the amygdala, hippocampus, subgenual cingulate cortex, and putamen.
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