Patients with fibromyalgia suffer from chronic pain, which limits physical activity and is associated with disturbed sleep. However, the relationship between physical activity, pain, and sleep is unclear.
The FDA has approved the first generics of Lyrica (pregabalin; Pfizer) capsules.
The presence of fibromyalgia may serve as a clinical sign of a more severe migraine.
There may be a bidirectional relationship between fibromyalgia and migraine.
There is disagreement between clinical diagnosis and criteria-based diagnosis of fibromyalgia.
Smoking tobacco is a risk factor for cognitive dysfunction in patients with fibromyalgia.
Transcutaneous electrical nerve stimulation administered during physical activity may effectively alleviate fibromyalgia-associated pain, fatigue, and disease impact in women.
The investigators hope that the BCG vaccine can increase anti-inflammatory cytokines, which are deficient in patients with fibromyalgia.
Geoffrey Littlejohn, MD, provides a clinical perspective on the pathophysiology of fibromyalgia and the role of neurogenic inflammation in the disease process.
Mirtazapine is a central alpha-2 antagonist currently FDA-approved for the treatment of major depressive disorder.
