Monoclonal Antibody Granted Orphan Drug Status for Frontotemporal Dementia
There are currently no treatments available for frontotemporal dementia.
Frontotemporal Dementia
MAPT H1 Haplotype Implicated in ALS Risk, With Genetic Overlap Between ALS and FTD
Investigators sought to identify genetic factors that may contribute to the risk for neurodegenerative diseases, such as amyotrophic lateral sclerosis and frontotemporal dementia.
Frontotemporal Dementia, Frontotemporal Lobar Degeneration Symptoms More Common Later in Life
The investigators hope that the findings from the study help raise awareness of frontotemporal dementia in geriatric patients.
Differentiating Dementia Subtypes With Transcranial Magnetic Stimulation
Using a transcranial magnetic stimulation approach might make it easier to distinguish Alzheimer’s disease from frontotemporal dementia.
When It’s Not Alzheimer’s: The Differential Diagnosis of Frontotemporal Lobar Degeneration
Neuroimaging and if necessary, genetic testing, can help to confirm an FTD diagnosis.
When It’s Not Alzheimer’s: Differential Dx of Frontotemporal Lobar Degeneration
Frontotemporal lobar degeneration (FTLD) refers to a group of non-Alzheimer’s dementias that cause portions of the frontal and temporal lobes to atrophy, leading to impairments in behavior, personality, language, and movement. FTLD is estimated to cause up to 10% of dementia cases, and it is the most common cause of dementia in individuals younger than…
Neural Networks Involved in Abnormal Eating in Dementia
Eating abnormalities in frontotemporal dementia result from a network of brain regions, rather than 1or 2 specific structures.
Boosting Proteasome Function May Prevent Spread of Tau Protein
Addressing proteasome dysfunction may help prevent accumulation of the toxic protein.
Nuclear Transport Disruption Linked to Amyotrophic Lateral Sclerosis
A gene mutation behind a large amount of ALS and FTD cases may disrupt nuclear transport, destroying neurons.
Mouse Model Developed for Common Form of ALS, Frontotemporal Dementia
The mouse model will allow researchers to effectively test therapeutic compounds.
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