Headache Archives - Neurology Advisor


Higher Nerve Sensitivity to Mechanical Stimuli in Tension-Type Headache

Women with vs without frequent episodic tension-type headache (TTH) may have greater nerve sensitivity in response to mechanical stimuli, according to a study in Musculoskeletal Science and Practice. In this case-control, cross-sectional analysis, 32 consecutive women with TTH and 32 age-matched control individuals without a history of headache over the previous year were recruited from…

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Investigational Ubrogepant Does Not Confer Hepatotoxicity in Healthy Individuals

Ubrogepant — a small-molecule, orally delivered, and specific calcitonin gene-related peptide receptor antagonist under investigation for acute treatment of migraine — features a favorable tolerability profile in healthy adults, study results published in Cephalalgia suggest. Calcitonin gene-related peptide receptor antagonism was previously shown to be effective in the acute treatment of migraine attacks. However, the…

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