Clinical Benefits of Multidisciplinary Rehabilitation in Premanifest HD
Participants in the multidisciplinary intervention group had significant improvements in verbal learning and memory, attention, cognitive flexibility, and processing speed.
Huntington Disease
Huntington Disease Brain Changes Found Years Before Symptoms
The earliest brain changes due to Huntington disease can be detected in cerebrospinal fluid 24 years before clinical symptoms show.
Most Huntington Disease Clinics Lack Resources to Administer Intrathecal Disease Modifying Therapies
Researchers find that many Huntington disease specialist clinics do not have the resources available to administer DMTs appropriately with an intrathecal strategy.
Patients With Huntington Disease Frequently Report Emotional Issues, Fatigue, and Difficulty Thinking
Researchers found emotional issues, fatigue, and difficulties in thinking represent common symptomatic themes in patients with Huntington disease.
The Role of Alcohol Consumption in Workplace Disability for Patients With Huntington Disease
In patients with Huntington disease, higher levels of functional impairment and current alcohol consumption were significantly correlated with missing work in multivariate logistic regression analyses.
New Diagnostic Criteria and Categories for Huntington Disease Proposed by Movement Disorder Society
The Movement Disorder Society Task Force recently published a proposal for new diagnostic criteria for 3 Huntington disease categories.
Most At-Risk Opt Out of Genetic Testing for Huntington Disease
The vast majority of people at risk for Huntington disease (HD) choose not to be tested preemptively, mainly because there is no cure for the disease.
Trial Supports Further Development of Huntington Antisense Oligonucleotide Therapy
Antisense oligonucleotide drug HTTRx reduced the concentration of mutant huntingtin protein in the cerebrospinal fluid of persons with Huntington disease.
Identifying Predictors of Suicidal Behavior in Huntington Disease
Researchers sought to identify variables that were associated with suicidal ideation or behavior in patients with Huntington disease.
HTT CAG Repeat Size, Age at Onset Associated With Huntington Disease Progression
Investigators sought to assess factors contributing to progression of functional, cognitive, and motor impairment in Huntington disease.
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