Aggressive Blood Pressure Lowering in Intracerebral Hemorrhage May Be Harmful
The avoidance of SBP <120 mm Hg in individuals with acute ICH may help prevent cerebral ischemia and neurologic deterioration.
Intracerebral Hemorrhage
Models Predict Intracerebral Hemorrhage Growth
Models using 4 or 5 predictors have acceptable to good discrimination for determining additional intracerebral hemorrhage growth in patients with acute intracerebral hemorrhage.
Increased Systolic Blood Pressure Variability Linked to Worse Neurologic Outcomes in Intracerebral Hemorrhage
The primary outcome was an unfavorable neurologic outcome, which was defined as a modified Rankin Scale score of 3 to 6 at 3 months following randomization.
Clinical, Radiologic Markers Predictive of Cortical Superficial Siderosis in ICH Identified
Investigators identify clinical and neuroimaging markers associated with the presence of cortical superficial siderosis and the risk for recurrent ICH.
Intracerebral Hemorrhage Risk Decreased With Increasing Cholesterol, Statin Use
An inverse relationship was discovered between rising cholesterol levels and decreased risk for intracerebral hemorrhage in new statin users.
Tranexamic Acid Provides Short-Term, But Not Long-Term, Benefits Following Intracerebral Hemorrhage
Patients with intracerebral hemorrhage who were admitted to acute stroke units were randomly assigned to either 1 gram intravenous tranexamic acid followed by an 8-hour infusion of 1 gram tranexamic acid or matched placebo.
Prediction Algorithm Stratifies ICH Patients at Risk for Hematoma Expansion
While developing the hematoma expansion prediction score, associations between hematoma expansion and blend sign, any intrahematoma hypodensity, and time from onset to noncontrast computed tomography <2.5 hours were found.
Cerebral Microbleeds Do Not Predict 3-Month Death or Disability in Intracerebral Hemorrhage
Investigators performed a pre-planned secondary analysis of the open-label, randomized Antihypertensive Treatment of Acute Cerebral Hemorrhage 2 study, specifically on the magnetic resonance images obtained during the intensive blood pressure lowering portion of the trial.
Predicting Hemorrhage Risk in Patients With Vascular Malformations
The investigators of this study did not compare pre- or post-hemorrhage data, precluding their ability to determine the applicability of the findings for improving clinical practice.
Intensive Blood Pressure Lowering Provides No Mortality Benefit in Acute Intracerebral Hemorrhage
Investigators conducted a meta-analysis of trials that reported functional outcomes and mortality rates among patients with intracerebral hemorrhage following intensive blood pressure lowering.
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