Treatment-Resistant Depression Linked to Cohabitation, Migraine, and More
In Denmark, investigators found data that showed many factors that were linked to treatment-resistant depression, including cohabitation, migraine, and so on.
Migraine
FDA Clears Hand-Held Vagus Nerve Stimulator for Migraine Prevention
The FDA has approved an expanded indication for the gammaCore device to include prevention of migraine.
Significant Reduction in Monthly Migraine Days Observed With Rimegepant in Prevention Trial
Biohaven announced positive topline results from a pivotal phase 2/3 study evaluating rimegepant for the preventive treatment of episodic and chronic migraine in adults.
Menstrual Migraine: Revisiting the Relationship Between Hormonal Events and Migraine
A narrative review summarizes recent data on the pathophysiology, epidemiology, and burden of disease and treatment of menstrual migraine.
Increasing Headache Day Frequency and Intensity Increases Risk of Additional Health Concerns
The presence of migraine and increasing headache pain intensity are associated with higher rates of anxiety, depression, inflammation, and sleep conditions, among other disorders.
Intranasal Ketamine Reduces Pain in Children Hospitalized for Migraine
A single-center study showed that intranasal ketamine effectively reduced pain in children with migraine from hospital admission to discharge.
Differences in Adverse Events in Phase 2 and Phase 3 Studies: The Case of Lasmiditan
Phase 2 clinical trials investigating lasmiditan reported higher incidence and severity of TEAEs, compared with the phase 3 studies.
Changes in Plasma Glucose Levels During Migraine Attacks
Plasma glucose levels are increased in patients with migraine with and without aura during spontaneous migraine attack compared with the interictal state.
FDA Approves Eptinezumab as First IV Preventive Migraine Therapy
The Food and Drug Administration has approved Vyepti (eptinezumab-jjmr; Lundbeck) for the preventive treatment of migraine in adults.
Can Functional MRI Aid in the Diagnosis of Migraine?
Distinct pattern of abnormal brain connection on fMRI can assist in the differentiation between a healthy brain and a brain with migraine without aura.
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