Benefits of Deep Brain Stimulation for Early Stage Parkinson Disease
Compared with optimal medical therapy alone, deep brain stimulation can decrease the risk for disease progression in patients with early-stage Parkinson disease.
Movement Disorders
Huntington Disease Brain Changes Found Years Before Symptoms
The earliest brain changes due to Huntington disease can be detected in cerebrospinal fluid 24 years before clinical symptoms show.
Reduced Circadian Rhythmicity Tied to Increase in Parkinson Disease
Results from a sleep study indicate a reduced circadian rhythmicity is associated with an increased risk for incident Parkinson disease.
Fractures More Common During Prodromal Period of Parkinson Disease
Researchers examined the association between fractures and Parkinson disease during the prodromal period.
Higher Doses of Deutetrabenazine Examined in Huntington Disease-Associated Chorea
Higher doses of deutetrabenazine appear to be safe and well tolerated in patients with Huntington disease who may require them to adequately control chorea.
Benefits Seen With Deutetrabenazine in Tardive Dyskinesia Regardless of Age
Treatment with deutetrabenazine was found to be beneficial for both younger (<55 years) and older (≥55 years) patients with tardive dyskinesia, according to findings from a recently published post hoc analysis.
Therapeutic Options for Peripheral Neuropathy in Parkinson Disease
The etiology and management of peripheral neuropathy in Parkinson disease is discussed.
Extended-Release Amantadine Under Review for Off Episodes in Parkinson Disease
The FDA has accepted for review the supplemental New Drug Application for Gocovri® for the treatment of off episodes in Parkinson disease patients receiving levodopa-based therapy.
Tobacco Smoking May Lower Risk for Parkinson Disease While Increasing the Risk of Other Illnesses
A study found a causally protective effect of tobacco smoking on the risk of Parkinson disease.
Sublingual Apomorphine Hydrochloride Approved for Off Episodes in Parkinson Disease
This sublingual film formulation of apomorphine was designed for use as a fast-acting, on-demand treatment for all types of motor off episodes.
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