Efficacy of Isradipine in Early-Stage Parkinson Disease
Researchers assessed the effect of isradipine on clinical progression in previously untreated patients with early-stage PD.
Movement Disorders
Abnormal Cerebral Blood Flow May Influence the Etiology of Parkinson Disease
Patients with Parkinson disease tend to have an increase in iron content with reduced perfusion in the substantia nigra.
Iron Deposition Provides Cognitive Clues in Patients With Parkinson Disease
Up to half of patients with Parkinson disease are also diagnosed with dementia, but tools to track changes in cognition are lacking.
Active Lifestyle May Lower Risk for Parkinson Disease
A physically active lifestyle is associated with a reduced risk for Parkinson disease (PD).
Benefits of Bladder Training for Lower Urinary Tract Symptoms in Parkinson Disease
Bladder training and conservative advice may improve lower urinary tract symptoms in patients with Parkinson disease.
Possible Molecular Signature for Young-Onset Parkinson Disease Identified
There is a distinct genetic signature for young-onset Parkinson disease even in cells from those who have no known Parkinson disease-related mutations.
Outpatient Palliative Care Improves Outcomes in Parkinson Disease
Compared with standard care alone, outpatient palliative care is associated with benefits among patients with Parkinson disease and related disorders.
Panel Delivers Consensus on Tardive Dyskinesia Diagnosis and Treatment
A group of tardive dyskinesia experts has concluded that individuals taking antipsychotics should receive regular assessments, tardive dyskinesia may be indicated by mild movements isolated to 1 body area, an overall assessment of treatment is required for management, and thorough caregiver/patient discussions are required.
Deep Brain Stimulation System Gains Expanded Approval for Parkinson Disease Management
The FDA has approved an expanded indication for the Infinity™ Deep Brain Stimulation (DBS) system (Abbott) to include targeting the internal globus pallidus, which may lead to symptom improvement in patients with Parkinson disease.
Gut Inflammation Linked to the Development of Parkinson Disease
A growing body of research points to the role of the gut-brain axis in the development of Parkinson disease, with inflammatory bowel disease, leaky gut, and altered gut microbiota observed in the gut, often years before the onset of symptoms of Parkinson disease.
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