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Movement Disorders

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CSF α-Synuclein Decreases Early in Drug-Naive Patients With Parkinson Disease

Cerebrospinal fluid (CSF) α-synuclein decreases early in untreated Parkinson disease (PD), yet α-synuclein does not appear to correlate with disease progression. This is according to a study in Movement Disorders. The ongoing, longitudinal study (Parkinson’s Progression Markers Initiative) included newly diagnosed, untreated patients with PD (n=423; mean age, 61.7 years) as well as age- and…

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