Neurocognitive Disorders Archives

Neurocognitive Disorders

Hyperuricemia, Gout Do Not Raise Dementia Risk

By

Jody A. Charnow

August 2, 2021

Hyperuricemia and gout may be associated with a lower risk for Alzheimer disease.

Neurocognitive Disorders

Vision Impairment Tied to Cognitive Decline

July 30, 2021

Worse visual acuity, contrast sensitivity, and stereo acuity impairment are associated with an increased risk for cognitive decline in older, community-dwelling individuals.

Neurocognitive Disorders

Screen Time Tied to Cognition, Behavior in Children Born Preterm

July 28, 2021

High amounts of screen time contribute to adverse cognitive, executive function, and behavior outcomes at ages 6 to 7 years in EPT children.

Movement Disorders

Procedural Sequence Learning, Event File Binding Mechanisms in Tourette Syndrome

By

Amit Akirov, MD

July 23, 2021

In this review, study researchers explained how procedural sequence learning and event file binding are 2 cognitive mechanisms underlying habitual behavior in Gilles de la Tourette syndrome.

Movement Disorders

Youth With Tourette Disorder-Associated Tic May Respond to Behavioral Therapy

By

Jessica Nye, PhD

July 21, 2021

Study researchers assessed the role of cognitive control processes in tic severity reduction, as well as treatment response to behavioral therapy in youth with Tourette disorder.

Seizures and epilepsy (≥2 unprovoked seizures) are more common in patients with APS compared with the general population.6,10 Between 3% and 10% of patients with APS have seizures/epilepsy, a prevalence that is 10 times greater than that of the general population.10 In half of these patients, epilepsy onset is after diagnosis.3 Epilepsy is more common in APS secondary to SLE vs primary APS (13.7% vs 6%; P <.05).11 Evidence of a correlation between aPL positivity and seizure is inconclusive.10 Seizures and epilepsy in patients with APS are primarily attributable to vascular disease.6 In a cohort study of 538 patients with APS, the odds ratio for epilepsy was 4.05 (95% CI, 2.05-8.00) in those with a prior central nervous system thromboembolic event.11 Epilepsy was also associated with higher rates of thrombocytopenia, livedo reticularis, and autoimmune hemolytic anemia.11 Some patients with APS with epilepsy have normal brain MRI results,3 and in vitro studies have implicated interactions between autoantibodies and neural structures.6

Neurocognitive Disorders

Consensus Needed to Address Inconsistency in Metrics and Definitions Used to Assess Cognitive Impairment in SLE

By

Inga Back, MPH

July 21, 2021

Researchers highlighted the importance of a consensus to address inconsistencies in the metrics and definitions used for cognitive impairment assessment in systemic lupus erythematosus.