Former Surgeons General Cite Dementia as Top Public Health Crisis
The United States has a rapidly ageing population, and 14 million people are projected to live with dementia by 2050.
Neurocognitive Disorders
ECT Effectively Reduced Agitation, Improved Functioning in Dementia
Researchers found ECT was a safe for patients with dementia experiencing agitation or aggression, as well as for those with comorbid medical conditions.
Antidepressant Monotherapy in Elderly Linked to Increased Incident Dementia
Although 11.0% of individuals taking antidepressants developed dementia, only 2.6% of the unexposed sample went on to be diagnosed with dementia.
Neflamapimod Gets Fast Track Status for Dementia With Lewy Bodies
The FDA has granted Fast Track designation to neflamapimod (EIP Pharma) for the treatment of dementia with Lewy bodies (DLB).
Long Sleep Duration Linked to Cognitive Decline Among Hispanic Individuals
Long sleep duration predicts seven-year cognitive decline among U.S. Hispanic/Latino patients.
Cortical Atrophy and Cognitive Decline Accelerated in Stable and Progressive Multiple Sclerosis
Cortical atrophy and cognitive decline accelerate together during the course of multiple sclerosis.
Aducanumab BLA to Be Submitted Following Positive Results in Early Alzheimer Trial
Compared with placebo, high dose aducanumab was associated with significant reduction of clinical decline in patients with early Alzheimer disease, as measured by the change from baseline in Clinical Dementia Rating-Sum of Boxes score at 78 weeks.
An Overview of HIV-Associated Neurocognitive Disorder
Rates of HIV-associated dementia have decreased from approximately 50% in the pre-cART era to 2% currently. However, roughly 50% of patients treated with cART have the milder forms of HIV-associated neurocognitive disorder (HAND).
Neurologic Impairment May Persist in HIV Encephalopathy Despite Potent ART
Despite potent antiretroviral therapy, HIV-associated dementia results in significant morbidity and mortality.
Early Adult Income Volatility Tied to Brain Health Later in Life
Income volatility during a 20-year period beginning in young adulthood is associated with worse cognitive function and brain integrity in midlife.
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