Early-Stage Alzheimer Disease Has Adverse Financial Consequences
Early-stage Alzheimer disease seems to put households at risk for large adverse changes in liquid assets and may reduce net wealth.
Neurodegenerative Diseases
Deaths Related to Neurodegenerative Disease Have Increased Among Former Soccer Players
Former soccer players have an increased risk for mortality from neurodegenerative diseases.
FDA to Review Satralizumab for Neuromyelitis Optica Spectrum Disorder
The FDA has accepted the Biologics License Application (BLA) for satralizumab (Genentech) for the treatment of neuromyelitis optica spectrum disorder.
Investigational Treatment for Guillain-Barré Syndrome Gets Fast Track Status
The FDA has granted Fast Track designation to ANX005 for the treatment of Guillain-Barré Syndrome, an autoimmune disease that can lead to widespread peripheral nerve damage and paralysis.
Women With Cardiometabolic Risk Factors More Vulnerable to Cortical Atrophy
The effects of cardiometabolic risk factors on cortical thickness are different between men and women, as women with these risk factors are more vulnerable to cortical atrophy than men.
Myobloc Approved for the Treatment of Chronic Sialorrhea
The Food and Drug Administration (FDA) has approved Myobloc (rimabotulinumtoxinB injection; US WorldMeds) for the treatment of chronic sialorrhea in adults.
Amyotrophic Lateral Sclerosis Risk and the Role of Genetics
Inherited and noninherited genetic factors contribute equally to the risk for developing amyotrophic lateral sclerosis (ALS), and first-degree relatives of people with ALS tend to have a higher risk for the disease compared with the general population, even in the absence of known ALS-associated genetic mutations.
Trial Investigating Fosmetpantotenate for Rare Neurologic Disorder Misses Primary End Point
A phase 3 trial evaluating an investigational therapy for the treatment of pantothenate kinase-associated neurodegeneration did not meet its primary or secondary end points.
Respiratory Function May Herald Progression of Amyotrophic Lateral Sclerosis
Three trajectories of respiratory function have been identified in patients with amyotrophic lateral sclerosis.
Focal Epilepsy Associated With Acceleration in Progressive Cortical Thinning
Focal epilepsy may accelerate widespread progressive cortical thinning to a greater degree than that observed in normal aging.
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