MRI-Based Small Vessel Disease Score Predicts Risk for Dementia
A simple SVD score using MRI scans, may aid in identifying patients with SVD who are likely to develop cognitive decline.
Neurodegenerative Diseases
Verdiperstat Fast-Tracked for Multiple System Atrophy
The Food and Drug Administration has granted Fast Track designation to verdiperstat (BVH-3241; Biohaven) for the treatment of multiple system atrophy.
Increased Serum NfL Indicates Ongoing Neuroinflammation, May Predict Neurodegeneration in Early MS
Serum NfL levels are indicative of ongoing neuroinflammation and may be predictive of neurodegeneration in patients with early MS.
Novel Therapy for Progressive Supranuclear Palsy Gets Orphan Drug Designation
The FDA has granted Orphan Drug designation to RT001 (Retrotope) for the treatment of progressive supranuclear palsy (PSP).
Predicting Amyloid Accumulation in Patients With Objective Subtle Cognitive Difficulties
The presence of objective subtle cognitive difficulties (Obj-SCD) on neuropsychological measures may predict faster amyloid accumulation and neurogenerative changes.
Inebilizumab Shows Promise in Neuromyelitis Optica Spectrum Disorder
Inebilizumab is superior to placebo in reducing the risk for a neuromyelitis optica spectrum disorder attack.
Riluzole Oral Film Approved for Amyotrophic Lateral Sclerosis
The FDA has approved Exservan (riluzole oral film; Aquestive Therapeutics) for the treatment of amyotrophic lateral sclerosis.
Shared Genetic Liability Observed for Psychosis in Alzheimer Disease
The study examined 3 psychotic phenotypes: psychosis wide, psychosis narrow, and delusions narrow.
Early-Stage Alzheimer Disease Has Adverse Financial Consequences
Early-stage Alzheimer disease seems to put households at risk for large adverse changes in liquid assets and may reduce net wealth.
Deaths Related to Neurodegenerative Disease Have Increased Among Former Soccer Players
Former soccer players have an increased risk for mortality from neurodegenerative diseases.
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