Is Dose Tapering Linked to Mental Health Crises in Setting of Long-Term, High-Dose Opioid Therapy?
Opioid dose tapering may be linked to increased risk for overdose and mental health crises in patients taking long-term, high-dose opioids.
Opioids
DEA Warns of Fentanyl in Counterfeit Opioid Pills
People buying pills that look like prescription opioid painkillers or stimulants who are not buying them from a licensed pharmacy may be buying a lethal drug.
Slight Decline Seen in Opioid Prescription Rates
Investigators assessed the impact of physician clinical knowledge on opioid prescribing habits following the shift in guideline recommendations away from opioid prescribing.
Perioperative Acetaminophen Increases Pain Outcomes After Shoulder Surgery
Perioperative acetaminophen significantly decreases opioid consumption and results in improved overall pain control following primary rotator cuff repair.
Kloxxado Now Available for Emergency Treatment of Opioid Overdose
Kloxxado is an opioid antagonist that delivers 8mg of naloxone hydrochloride per spray into the nasal cavity.
State Limits on Initial Opioid Rx Duration May Influence Prescribing
State laws restricting the duration of initial opioid prescriptions are associated with changes in opioid prescribing.
22.1% of US Adults With Chronic Pain Use Rx Opioids
In 2019, 22.1 percent of U.S. adults with chronic pain reported using a prescription opioid in the previous three months.
Almost Half of Pediatric Opioid Prescriptions Considered High-Risk
Almost half of pediatric opioid prescriptions are considered high-risk by one or more metric, and high-volume prescribers write more than half of the prescriptions.
Robust Prescription Monitoring Programs Influence Discontinuation of Long-Term Opioid Use Patterns
A Weill Cornell Medicine team analyzed Health Care Cost Institute database claims, with opioid prescription gaps ≥30 days considered long-term nonuse.
JACC Review Highlights Cardiovascular Outcomes Associated With Acute and Chronic Opioid Use
This review explores the cardiovascular consequences of opioids and the contributions of off-target electrophysiologic properties to mortality, and provides practical safety recommendations.
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