FDA Rejects Intravenous Tramadol Over Potential Safety Concern
The FDA stated that IV tramadol is not safe for the intended patient population.
Opioids
Managing Analgesia in Critically Ill Patients Receiving Naltrexone
Researchers convened to develop recommendations on management of sedation and analgesia in critically ill patients receiving naltrexone for opioid use disorder.
Recovery Protocol Cuts Opioid Use After Elective Neurosurgery
Cohort study shows reduced opioid use for patients having elective spine and peripheral nerve surgery.
Orphengesic Forte Now Available for Pain Management
The safety of long-term Orphengesic Forte use has not been established.
New IV Opioid Analgesic Approved for Acute Pain
Olinvyk is indicated for short-term intravenous use in hospitals or other controlled clinical settings.
Combination Interventions Needed to Tackle Excess Mortality From Extramedical Opioids
Excess mortality occurred as the result of a number of causes, including overdose, injuries, and both infectious and noncommunicable diseases.
Opioid-Related Unintentional Deaths and Suicides Have Increased Since 2000
Between 2000 and 2017, unintentional deaths and suicides related to opioid use have increased substantially, whereas overall deaths from suicide have decreased.
Navigating Patient Pain Under Stricter Opioid Prescribing Laws
Investigators explored concerns with regard to opioid prescribing in compliance with new regulations in a commentary piece.
Kratom Seems Safe for Pain, Anxiety, Opioid Withdrawal
Kratom is used for symptoms of pain, anxiety, depression, and opioid withdrawal, and serious adverse events are uncommon.
Long-Term Neurodevelopmental Impacts of Prenatal Opioid Exposure
Perinatal exposure to opioids may have significant immune, neural, and behavioral effects that can alter CNS development.
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