Enrollment in Fibromyalgia Treatment Study Ends After Disappointing Results
The phase 3 RALLY study is evaluating the efficacy and safety of TNX-102 SL in 514 adult patients with fibromyalgia.
Pain Management
JACC Review Highlights Cardiovascular Outcomes Associated With Acute and Chronic Opioid Use
This review explores the cardiovascular consequences of opioids and the contributions of off-target electrophysiologic properties to mortality, and provides practical safety recommendations.
Virtual Roller Coaster Ride Used to Study Migraine Symptoms
Migraine patients report significantly more dizziness and motion sickness than controls during a virtual roller coaster ride.
Broad Range of Drug-Drug Interactions in Migraine Prevention and Treatment
Researchers conducted a narrative review of the pharmacokinetics of major classes of migraine preventives and the implications of drug-drug interactions in treatment.
FDA Approves Spinal Cord Stimulation Therapy for Painful Diabetic Neuropathy
The FDA has approved the Senza® Omnia spinal cord stimulation system for the treatment of chronic pain associated with PDN.
Low-Intensity Focused Ultrasound May Safely, Effectively Treat Chemo-Induced Peripheral Neuropathy
The researchers’ goal was to evaluate the effectiveness of low-intensity focused ultrasound (LIFU) therapy in the management of cancer-related neuropathic pain (CNP).
Trigeminal Neuralgia: A Rare Facial Pain Condition Comprising 3 Distinct Subtypes
Study researchers conducted a narrative review to update the public on the new classification of trigeminal neuralgia, clinical signs, pathophysiology, and management.
Many Effective Therapies for Acute Migraine Pain but Little Evidence Supports Use of Opioids
The researchers’ goal was to weigh the risks and benefits of acute treatments for episodic migraine in adults.
Benefit, Safety of Muscle Relaxants for Low Back Pain Uncertain
Considerable uncertainty exists about the clinical efficacy and safety of muscle relaxants for the treatment of low back pain.
Consensus-Based Management of Opioid Misuse, Opioid Use Disorder in Cancer
A team of investigators conducted a Delphi study to provide evidence-based guidance to clinicians about management and care of patients with serious illnesses who misuse opioids or have opioid use disorder.
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