Review Explores Risk for Early-Onset Stroke, Parkinson Disease With Methamphetamine Use
The review authors sought to elucidate the neurological harms of methamphetamine, which are well-documented but poorly understood.
Parkinson Disease
Solriamfetol May Improve Sleep Latency Among Patients With Parkinson Disease
This phase 2, double-blind trial of solriamfetol evaluated the dose-dependent effects on sleep latency in patients with Parkinson disease.
Gel Formulation of Neuroactive Drugs for Parkinson Disease Administered Intranasally May Be More Effective Delivery Method
The study researchers reported on a self-assembled hydrogel to deliver the drug 4-dihydroxyphenylalanine (L-DOPA) for Parkinson disease.
Long-Term Low-Dose Sargramostim Therapy Restores Immune Homeostasis in Parkinson Disease
Because sargramostim therapeutic use has been offset by dose-dependent adverse events, the researchers performed a reduced drug dose regimen to evaluate safety and to discover novel disease-linked biomarkers during sargramostim treatments for 1 year.
Parkinson Disease Linked to Exposure to Nitrogen Dioxide Air Pollutants
The researchers’ goal studied whether exposure to particulate matters, nitrogen dioxide, ozone, sulfur dioxide, or carbon monoxide raises the risk of Parkinson disease.
Essential Tremor: Implications in Heterogeneous Motor Phenomenology
A team of investigators observed people with essential tremor and their relatives to determine the relationship between essential tremor, Parkinson disease, and dystonia.
Benefits of Deep Brain Stimulation Persist in Parkinson Disease
For patients with PD, deep brain stimulation of the subthalamic nucleus (STN-DBS) is effective beyond 15 years after implantation.
Addressing Sleep Disturbances of Parkinson Disease
Sleep disturbances may affect 40% to 90% of patients with PD, and a 2020 study found that about half of patients with PD had multiple sleep disorders.
Vitamin-Responsive Neurogenetic Diseases: Role in Disease, Tests, and Future Directions
This review outlined clinical situations when diagnostic tests should be conducted for vitamin-responsive inherited diseases and when vitamins should be administered for optimal disease outcomes.
Systemic Monocyte Activation Patterns in Early Parkinson Disease Appear to Differ by Sex
To better understand the relationship between peripheral blood monocyte activation and PD, investigators recruited a population of patients with untreated early PD.
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