First Generic Versions of Fingolimod Gain FDA Approval
The FDA has approved the first generic versions of fingolimod for the treatment of relapsing forms of multiple sclerosis in adults.
Relapsing Remitting Multiple Sclerosis
Cortical Atrophy and Cognitive Decline Accelerated in Stable and Progressive Multiple Sclerosis
Cortical atrophy and cognitive decline accelerate together during the course of multiple sclerosis.
Diroximel Fumarate Approved for Relapsing Forms of Multiple Sclerosis
Vumerity (diroximel fumarate; Biogen) has been approved for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease and active secondary progressive disease.
Patients With Multiple Sclerosis Experience a Wearing-Off Effect During Natalizumab Treatment
More than half of patients with multiple sclerosis experienced a wearing-off effect during treatment with natalizumab.
Therapeutic Potential for Subcutaneous Ofatumumab in Relapsing Multiple Sclerosis
The results of the identically designed ASCLEPIOS I and II phase 3 trials evaluating the effect of ofatumumab versus teriflunomide in participants with relapsing multiple sclerosis were presented at ECTRIMS 2019.
Diroximel Fumarate for Relapsing Remitting MS Shows Good Tolerability in Phase 3 Study
Treatment with diroximel fumarate was associated with significantly fewer days of key gastrointestinal symptoms, according to topline results from a phase 3 study evaluating the GI tolerability.
Positive Data for Ponesimod in Relapsing Multiple Sclerosis Study
Janssen announced positive top-line results from the phase 3 OPTIMUM study of ponesimod in adult patients with relapsing multiple sclerosis.
Focused Healthcare Practitioner Discussion Improves MS Relapse Outcomes
Interactive discussions with healthcare practitioners (HCPs) and patient education regarding multiple sclerosis (MS) relapse increases the likelihood of patients reporting relapses and achieving more proactive disease management
Structured Algorithm to Optimize Relapse Management in Multiple Sclerosis
The clinician workgroup achieved a consensus and report a 3-step iterative management algorithm for MS relapses.
Multiple Sclerosis Relapse Rate Linked to Puberty in Boys
Boys with onset of MS during puberty experienced an increased rate of relapse compared with boys with MS onset before or after puberty.
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