Is Iron Therapy an Effective Treatment for Restless Legs Syndrome?
The aim of the review was to assess the safety and efficacy of oral and parenteral iron for the treatment of RLS.
The aim of the review was to assess the safety and efficacy of oral and parenteral iron for the treatment of RLS.
For patients with restless leg syndrome, the primary motor cortex (M1) exhibits hyperexcitability, which is associated with disease severity.
Compared with control patients, patients with restless leg syndrome symptoms experienced a morphologic change in the brain somatosensory system.
Women with RLS are more likely to have cardiovascular-related comorbidities than those without RLS.
For patients with restless leg syndrome, opioids may be very beneficial if taken in low daily doses.
Few head-to-head trials have been conducted that have compared different classes of drugs for treatment of RLS.
RLS symptoms can be improved by nerve decompression for peripheral neuropathy.
Gabapentin enacarbil (Gen) administered once daily to patients with severe primary RLS significantly improved sleep, mood, pain, and quality of life.
Musculoskeletal pain, especially in the shoulder/arm and leg, is significantly associated with RLS.
Risk appeared to be correlated with RLS disease duration.