Is Iron Therapy an Effective Treatment for Restless Legs Syndrome?
The aim of the review was to assess the safety and efficacy of oral and parenteral iron for the treatment of RLS.
Restless Leg Syndrome
Increased Corticomotor Excitability ID’d in Restless Legs
For patients with restless leg syndrome, the primary motor cortex (M1) exhibits hyperexcitability, which is associated with disease severity.
Morphologic Changes in Primary Somatosensory System May Fuel Restless Leg Symptoms
Compared with control patients, patients with restless leg syndrome symptoms experienced a morphologic change in the brain somatosensory system.
Restless Legs Syndrome Associated With Increased Cardiovascular Mortality
Women with RLS are more likely to have cardiovascular-related comorbidities than those without RLS.
Guidelines: Opioids for the Treatment of Refractory Restless Legs Syndrome
For patients with restless leg syndrome, opioids may be very beneficial if taken in low daily doses.
Restless Leg Syndrome Equally Responsive to Multiple Drug Classes
Few head-to-head trials have been conducted that have compared different classes of drugs for treatment of RLS.
Surgical Nerve Decompression May Improve Restless Leg Syndrome
RLS symptoms can be improved by nerve decompression for peripheral neuropathy.
Gabapentin Enacarbil Effective In Treating Severe Restless Leg Syndrome
Gabapentin enacarbil (Gen) administered once daily to patients with severe primary RLS significantly improved sleep, mood, pain, and quality of life.
Multi-Site Musculoskeletal Pain Linked to Restless Legs Syndrome
Musculoskeletal pain, especially in the shoulder/arm and leg, is significantly associated with RLS.
Restless Legs Syndrome Ups Risk of Cerebral Microvascular Disease
Risk appeared to be correlated with RLS disease duration.
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