Evaluating the Role of Genetics in Pediatric Suicidal Ideation and Aggression
The use of genetic evaluation for suicidal ideation may represent a future application for precision medicine.
Suicide and Self-Harm
Spravato Approved for MDD With Acute Suicidal Ideation or Behavior
The approval was based on the ASPIRE I and II trials that compared the efficacy and safety of esketamine, an N-methyl-D-aspartate receptor antagonist, to placebo in 449 adults with moderate to severe MDD who had active suicidal ideation and intent.
Antidepressant Trials Often Exclude Patients Displaying Suicidality, Study Finds
Of all the antidepressant efficacy trials conducted between 1991 and 2013, just 1 explicitly included patients who presented with suicidality.
FDA Bans Electrical Stimulation Devices for Self-Injurious, Aggressive Behavior
The use of electrical stimulation devices to treat self-injurious or aggressive behavior has been banned by the Food and Drug Administration.
Opioid-Related Unintentional Deaths and Suicides Have Increased Since 2000
Between 2000 and 2017, unintentional deaths and suicides related to opioid use have increased substantially, whereas overall deaths from suicide have decreased.
Oseltamivir Not Linked to Increase Risk for Neuropsychiatric Events
No difference was seen in the risk for serious neuropsychiatric events in patients who received oseltamivir in the 30 days after influenza diagnosis compared with those who did not.
Suicide Rates Higher for Individuals With Neurological Disorders
Rates of suicide are significantly higher for individuals diagnosed with a neurological disorder versus the general population.
Comorbid PTSD Raises Risk for Suicidal Ideation in Patients with Bipolar Disorder
Compared with patients without PTSD, patients with both bipolar disorder and PTSD were more likely to be women, on disability, have a lower education level, and have a lower annual household income.
Significant Rates of Mistreatment, Burnout, and Suicidal Thoughts Observed Among Surgical Residents in the US
Cross-sectional study data published in the New England Journal of Medicine indicate that discrimination, abuse, and harassment are highly prevalent in surgical residency training, especially in female residents.
Depression, Anxiety, and Irritability Mediate Suicidality in Children with ADHD
After controlling for depression, irritability, and anxiety, the investigators found no direct effect of ADHD symptoms on suicidality.
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