The Handoff is a weekly roundup of neurology news covering various developments in subspecialties, the pharmaceutical industry, and the overall state of health care as it affects neurologists.
— Several trials exploring the use of gene therapy for the treatment of Duchenne muscular dystrophy are about to start, using a micro version of the dystrophin gene.
— The European Stroke Organization has updated its guidelines for the diagnosis and treatment of cerebral venous thrombosis. The guidelines have been endorsed by the European Academy of Neurology.
— Amneal Pharmaceuticals has issued a voluntary recall of 13 lots of lorazepam oral concentrate after it was discovered that the droppers may have dose marking defects.
— Despite strong concerns and effort by the FDA, a flawed study study of Sapepta’s controversial Duchenne muscular dystrophy drug eteplirsen remains published.
— After 2 years of debate, President Trump signed the FDA Reauthorization Act of 2017, securing the agency’s user fee program through 2022.
— Maine has implemented a law that limits opioid prescribing. While it required some tweaks, it seems to be working, motivating more physicians to offer alternative treatments.
— Many carriers of the APOE4 gene have taken so-called Alzheimer’s prevention into their own hands as unproven strategies for slowing or preventing cognitive decline abound.
— Check out this grand rounds from the University of Colorado School of Medicine on physician-assisted suicide in neurology. They review the clinical, ethical, and legal factors of the argument.