Best Oral Anticoagulants for Patients With CKD
Investigators sought to determine the safety and efficacy of novel oral anticoagulants to treat patients with chronic kidney disease, particularly with regard to cardiovascular outcomes.
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Peripartum Neuraxial Analgesia and Postpartum MS Relapse
Peripartum neuraxial analgesia may not be associated with an increased risk for multiple sclerosis relapse.
Stroke Risk Linked to Long Working Hours
Individuals with long working hours (LWHs) have an increased risk for stroke, with a stronger correlation for those exposed to LWHs for 10 years or more.
Recommendations for Screening, Rating Impulse Control Disorders in PD
International Parkinson’s and Movement Disorder Society released recommendations on clinical screening instruments and rating scales used to measure impulsive and compulsive behaviors in Parkinson disease.
Gene Therapy Granted Fast Track Status for CLN1 Disease
The investigational therapy works by delivering a working copy of CLN1 gene using an a one-time adeno-associated virus 9 vector platform.
Antiviral Therapy May Lower PD Risk in Chronic HCV
Investigators sought to determine the risk for Parkinson disease development in patients with hepatitis C virus who received antiviral treatment and in patients who did not receive this treatment.
Cognitive Consequences Worse for Pediatric-Onset MS
Researchers compared long-term information-processing efficiency between patients with pediatric-onset MS and those with adult-onset MS in a longitudinal cohort study.
Adhansia XR Soon to Be Available for ADHD
Adhansia XR (methylphenidate HCl extended-release capsules) is expected to be available as of July 15, 2019 for the treatment of attention deficit hyperactivity disorder (ADHD) in patients 6 years of age and older, according to Adlon Therapeutics.
Duration of PSSE Associated With Development of Post-Stroke Epilepsy
There is a higher likelihood of the development of post-stroke epilepsy in patients who had longer duration of early-onset post-stroke status epilepticus.
Migraine Associated With Abnormal Thalamo-Cortical Networks, Dysrhythmia
Adults with migraine have abnormal thalamo-cortical networks and dysrhythmia along with migraine-related deficits in brain function.
Online Access to Doctors Visit Notes Boosts Medication Adherence
Researchers analyzed patients’ perceptions of how reading physicians’ notes online influences factors associated with medication adherence.
Nilvadipine Increases Cerebral Blood Flow in the Hippocampus
For patients with mild-to-moderate Alzheimer disease, treatment with nilvadipine lowers systolic blood pressure and increases cerebral blood flow (CBF) in the hippocampus.
Drug Makers Challenge New Rule Requiring Drug Prices in TV Ads
Three large drug makers have launched a legal challenge against the Trump administration’s rule requiring the prices of drugs to be included in television ads.
Wakefulness Promoter Sunosi Designated Schedule IV Controlled Substance
The Drug Enforcement Agency (DEA) has designated Sunosi (solriamfetol; Jazz Pharmaceuticals) a Schedule IV controlled substance.
Cognitive Decline Faster After Incident Coronary Heart Disease Event
Incident coronary heart disease (CHD) is associated with accelerated cognitive decline after, but not before, the event.
Rotavirus Infection Linked to Corpus Callosum Lesions in Infantile Seizure Disorder
A study found that rotavirus infection is associated with lesions in the splenium of the corpus callosum in patients with benign convulsions with mild gastroenteritis.
Perinatal Maternal Depression Linked to Child Brain Development
Perinatal maternal depressive symptoms were consistently associated with brain development in offspring at age 10 years.
Midlife Diabetes Increases Cerebral Infarction, Arterial Occlusion Risk
Patients with midlife type 2 diabetes have a significantly increased risk for cerebral infarction and occlusion of cerebral arteries later in life.
Head, Facial Injuries From Motorized Scooters on the Rise
Facial and head injuries from electric scooter accidents have tripled during the past decade.
Prenatal AED Exposure Puts Child at Increased Risk for Behavioral Problems
Findings seen among Dutch children exposed to one of four common antiepileptic drugs in utero. Researchers noted high percentages of children with clinically relevant behavior problems across all four antiepileptic drug exposure groups.
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