Risk for Encephalopathy in Patients With CKD Using Baclofen
Initiating baclofen treatment at a high dose may be associated with increased 30-day incidence of encephalopathy in older adults with chronic kidney disease.
Topics
Spending on DMTs for MS Increased From 2011 to 2017
From 2011 to 2017, there was an increase in gross annual expenditures on multiple sclerosis (MS) disease-modifying therapies (DMTs), with increased spending mainly driven by increases in per-prescription costs.
Video Game Based Digital Therapy Looks Promising in Pediatric ADHD Trial
Akili Interactive announced topline data from an open-label study (STARS-ADHD Adjunctive) of AKL-T01 for the treatment of attention deficit hyperactivity disorder in children with or without use of stimulants.
One in Four Children With Autism Not Formally Diagnosed
Autism spectrum disorder (ASD) remains underdiagnosed in black and Hispanic children.
Acupuncture Proved More Effective Than Standard Care in Reducing Tx-Induced Xerostomia
True acupuncture is more effective than placebo and standard care in reducing the number and severity of radiation-induced xerostomia (dry mouth) symptoms at 1 year following treatment in patients with head and neck cancer.
Interictal Burden of Cluster Headache Greatly Affects Disease Burden and Quality of Life
Survey findings suggest that cluster headache attacks can negatively affect an individual’s career, education, and social life.
FDA Committees Vote on Novel Opioid for Chronic Low Back Pain
As a result of the vote, Nektar has decided to withdraw the New Drug Application for oxycodegol and to cease further development of the product.
OSA May Predict Poor Outcomes in Ruptured Intracranial Aneurysms
Obstructive sleep apnea may represent a significant predictor of unfavorable outcomes in ruptured intracranial aneurysms.
Insomnia, Sleep Disturbances Common Among Veterans With PTSD
The researchers analyzed data from 1649 combat-exposed United States military veterans who were evaluated at a Veterans Affairs facility between 2009 and 2012 after deployment to the wars in Iraq and/or Afghanistan.
Clinical Pearls and Pitfalls of Automated CT Perfusion for Acute Ischemic Stroke
Researchers find automated CT perfusion is an important tool in the triage and treatment decision making in acute ischemic stroke.
Ubrogepant Superior to Placebo for Increasing Pain Freedom in Moderate, Severe Migraine
Acute treatment of migraine with ubrogepant, an oral calcitonin gene-related peptide antagonist, was superior to placebo for migraine pain freedom.
Dress for Success: Physician Attire May Influence Patients’ Perception of Care
First impressions are an important part of the patient-physician relationship, because they can affect the quality of the relationship well beyond the initial encounter.
Active Lifestyle May Protect Against Familial Frontotemporal Dementia
A physically and mentally active lifestyle may protect against frontotemporal dementia even in people at established genetic risk.
Diazepam Nasal Spray Approved for Seizure Clusters
The FDA has approved Valtoco (diazepam nasal spray; Neurelis) for the acute treatment of intermittent, stereotypic episodes of frequent seizure activity that are distinct from a patient’s usual seizure pattern in patients with epilepsy 6 years of age and older.
Antipsychotic Initiation Increases Risk for Head Injury, TBI in Alzheimer Disease
Individuals with Alzheimer disease (AD) initiating antipsychotics have an increased risk for head injuries and traumatic brain injury.
Why Are Unnecessary Lumbar Spine MRIs Ordered in Primary Care?
A study investigated the factors that add to unnecessary lumbar spine MRIs in uncomplicated low-back pain.
Lamotrigine Recalled Due to Cross-Contamination
Taro Pharmaceuticals announced the voluntary recall of 1 lot of lamotrigine 100mg tablets to the consumer level due to cross-contamination with a small amount of enalapril maleate.
Ryanodex NDA Resubmitted for Exertional Heat Stroke
In July 2017, Eagle had received a Complete Response Letter (CRL) from the FDA stating that an additional clinical trial would be needed prior to approval for the indication.
Early Concussion Treatment Linked to Faster Recovery
Earlier initiation of clinical care is associated with faster recovery after concussion.
Nerve Volumes Predict Surgical Outcome in Patients With Trigeminal Neuralgia
Larger contralateral trigeminal nerve and hippocampus volumes are predictive of early nonresponse to surgical treatment of trigeminal neuralgia.
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