CSF Orexin-A Levels Linked to Sleep Stability in Hypersomnolence
Cerebrospinal fluid orexin-A levels are associated with markers of nocturnal sleep stability in patients with hypersomnolence.
Topics
Survey Finds Variation in Practice Patterns for Neuroimaging in Sickle Cell Anemia
Survey finds variation in practice patterns for obtaining MRI/MRA for stroke prevention and monitoring in patients with sickle cell anemia.
FDA Requires Boxed Warning Update for Benzodiazepines
Benzodiazepines are widely used to treat a variety of conditions including anxiety disorders, insomnia and seizures.
Stroke 'Alarm Clock' Improves Acute Stroke Management Metrics
Use of a stroke alarm clock demanding active feedback significantly improves management metrics for acute stroke.l
Immunotherapy for Disability in Active Secondary Progressive MS
In patients with active relapses in secondary progressive multiple sclerosis, disease-modifying therapies improved disability outcomes.
Study Suggests Smoking Causes Fatal Subarachnoid Hemorrhage
Smoking seems to have a causal role in subarachnoid hemorrhage death compared with nonsmoking.
Meta-Analysis Links PTSD to Increased Dementia Risk
Risk up in veterans and general population, remains significant after exclusion of high-bias studies
Early, Continuous Ocrelizumab Therapy Reduces Relapsing MS Progression
Early, continuous ocrelizumab was related to a sustained reduction of relapsing MS progression compared with patients who switched from IFN β-1a.
Lasmiditan Increases Odds of Freedom From Migraine Attacks
Lasmiditan is associated with greater odds of achieving pain freedom from migraine attacks compared with placebo.
dCBT Reduced Symptoms of Insomnia in Norwegian Adults
This study investigated the effect of a fully automated dCBT program on insomnia severity, sleep–wake patterns, sleep medication use, and daytime impairment.
Elderly Social Isolation, Loneliness in COVID-19 May Lead to Cognitive Decline
Social isolation and loneliness can increase the risk for cognitive decline in seniors in assisted living or nursing homes during the COVID-19 pandemic.
Managing Analgesia in Critically Ill Patients Receiving Naltrexone
Ketamine infusion significantly decreased seizure burden within 24 hours in patients with super-refractory status epilepticus.
Managing Analgesia in Critically Ill Patients Receiving Naltrexone
Researchers convened to develop recommendations on management of sedation and analgesia in critically ill patients receiving naltrexone for opioid use disorder.
Fremanezumab Found to Reduce Number of Migraine Days in Chronic Migraine With Comorbid Depression
A pooled analysis evaluated reductions in migraine and headache days among patients with chronic migraine and comorbid depression in 2 placebo-controlled, phase 3 trials of fremanezumab.
Pregnancy May Delay Onset of Multiple Sclerosis Symptoms
The researchers found that the mean age at CIS onset was 31.5 years. Before CIS onset, 46 percent of women had at least one pregnancy and 43 percent had at least one childbirth.
Amygdala Connectivity May Predict CBT Efficacy for Adolescent Migraine
Connectivity between the amygdala and specific brain regions may predict headache reduction after cognitive behavioral therapy for adolescent migraine.
SSRI Use After ICH May Raise Risk of Recurrent Stroke
SSRI use after intracerebral hemorrhage may resolve depression symptoms, but also increases patients’ risk for recurrent stroke.
Inverted U-Shaped Link Seen for Sleep Duration, Cognitive Decline
There is an inverted U-shaped association between sleep duration and global cognitive decline.
Stress, Depressive Symptoms Up With Increasing COVID-19 Deaths
Acute stress and depressive symptoms have increased as COVID-19 deaths increased across the United States, with COVID-19-related media exposure and secondary stressors associated with these symptoms.
Endovascular Stroke Therapy More Beneficial On-Site Than Off-Site
Endovascular stroke therapy was shown to be more beneficial on-site than after transfer in patients with acute ischemic stroke.
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