The Impact of Weight Loss on Migraine Characteristics in Patients With Obesity
Among patients with obesity and migraine, weight loss is associated with reduction of migraine frequency, pain severity, and attack duration and disability.
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Psoriasis Linked to Increased Migraine Risk
Researchers analyzed the relationship between migraines and psoriasis in the general US population, using data obtained from the 2003-2004 National Health and Nutrition Examination Survey (NHANES).
Ofatumumab Under Review for Relapsing Forms of MS
The FDA has accepted for Priority Review the supplemental Biologics License Application (sBLA) for ofatumumab (Novartis) for the treatment of relapsing forms of multiple sclerosis (RMS) in adults.
Brain Amyloid Deposition and Intracranial Atherosclerotic Disease in Adults
There is no evidence for an association between cerebral β-amyloid deposition, a marker of Alzheimer disease, and intracranial atherosclerotic plaque or stenosis.
Compliance With FDA Reporting Guidelines for Clinical Trials Is Low, Not Improving
Cohort study data from 2018 to 2019 suggest poor compliance with the US Food and Drug Administration reporting requirements for clinical trial sponsors.
Multiple Sclerosis Susceptibility Associated With Certain Gut Bacteria
A network of gut bacteria species may be associated with host genetic factors that increase susceptibility to multiple sclerosis.
Natalizumab Linked to Disability Improvement in Early Relapsing-Remitting MS
More patients with early relapsing-remitting multiple sclerosis (RRMS) treated with natalizumab experienced confirmed disability improvement than disability worsening.
Hyperlipidemia Onset May Occur Earlier in Patients With Multiple Sclerosis
The onset of hyperlipidemia may occur earlier in patients with multiple sclerosis.
Patients Receiving Treatment for MS Have Increased Infection Risk
Patients who have been diagnosed with and treated for multiple sclerosis (MS) have an increased risk for any type of infection, with the highest risk being for renal tract infections.
Shared Genetic Variants Associated With Migraine and Multiple Sclerosis
Researchers sought to find any genetic variants associated with migraine or MS that could be identified from genome-wide association studies.
Fatigue, Anemia, Pain, Sleep Disorders Found to Be Part of MS Prodrome
Fatigue, anemia, pain, and sleep disorders form part of the prodrome in MS.
Telehealth May Be Safe and Feasible for Veterans With MS
Home telehealth may be a feasible and safe option for veterans with multiple sclerosis who have difficulty accessing services from the VA or community services.
Risks for Cardiac Outcomes Found to Be Higher in Patients With MS
Patients with vs without multiple sclerosis were found to be at increased risk for several cardiac events.
Multiple Sclerosis Outcomes Worsened When Youths Transition to Adult Care
Roughly half of patients with pediatric-onset multiple sclerosis (MS) who transition to adult clinics experience worsened clinical disability.
New Pediatric MS Therapies More Effective Than Injectables
Using newer disease-modifying therapies for the initial treatment of pediatric multiple sclerosis may be more effective than injectables at controlling disease activity.
Depression Linked to High Future Disease Activity Risk for MS
The researchers concluded that patients with both MS and depression experience worsening in neurological function, relapses, and lesions activity after 1 year compared with patients without depression.
STOP-Bang Questionnaire Effective for OSA Screening in MS
Researchers of the study assessed the sensitivity and specificity of the STOP-Bang tool in patients with MS.
Synthetic CBD Derivative EHP-101 Ready for Clinical Studies in MS
In this study presented at ACTRIMS Forum 2020, researchers evaluated the safety, tolerability, pharmacokinetics, and exploratory pharmacodynamics of EHP-101, an oral formulation of VCE-004.8.
Pediatric-Onset Multiple Sclerosis: Gut Microbiota and Relapse Risk
Pediatric patients with multiple sclerosis (MS) and a high relative abundance of Pasteurellales or Enterobacteriales in their gut microbiota have a lower relapse risk.
Test for Fragile X Syndrome Screening, Diagnosis Gets FDA Clearance
A diagnostic test for fragile X syndrome (FXS) has been cleared by the Food and Drug Administration.
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