Ponesimod Superior to Teriflunomide in Relapsing MS Trial
Ponesimod significantly reduced ARR by 30.5% when compared with teriflunomide (ARR=0.202 for ponesimod 20mg vs 0.290 for teriflunomide 14mg, P =.0003).
Topics
Link Between Lesion Location and Obstructive Sleep Apnea in MS
The risk for development of obstructive sleep apnea (OSA) and the severity of disease in patients with multiple sclerosis (MS) may be affected by the location of the lesions.
Reducing Risk for Relapse in Women with RRMS
Among women with active relapsing-remitting multiple sclerosis, continuation of natalizumab treatment until the end of the first trimester is associated with significantly reduced disease reactivation compared with stopping natalizumab at conception.
Improving Satisfaction in Patients With MS Via the First Diagnostic Consultation
Limited data are available regarding the satisfaction of patients with MS with their first diagnostic consultation (FDC). The goal of the current retrospective study was to identify FDC factors that may influence patient satisfaction.
The Economic Impact of Multiple Sclerosis
Multiple sclerosis seems to prevent individuals from realizing their full potential at home and work, with fatigue being overwhelmingly identified as the cause, according to preliminary findings presented at ECTRIMS 2019.
Reconsidering the Safety of IV Thrombolysis for Ischemic Stroke After Recent MI
Intravenous tissue-type plasminogen activator for acute ischemic stroke may be given to patients with recent or concurrent MI, but consideration should be given to the type of MI and time elapsed between the events.
Serum Biomarker Linked to Brain Atrophy in Multiple Sclerosis
Serum neurofilament light chain (sNFL) levels are significantly associated with clinical and neuroimaging outcomes in multiple sclerosis.
Worse Cervical Muscle Performance Found in Women With Migraine
Women with migraine are more likely to present with worse performance of the cervical muscles, both in force production and muscle activity, compared with women without migraine.
Majority of Those Diagnosed With Dementia Do Not Receive Care From Specialist
The majority of older adults diagnosed with dementia do not receive specialty care.
Diagnostic Delay Not Associated With Visual Symptoms in Giant Cell Arteritis
The study compared general and giant cell arteritis-specific characteristics in patients with and without visual symptoms, and examined the role of diagnostic delay in patients with giant cell arteritis experiencing current visual symptoms.
Highly Sensitive Imaging for the Characterization of Nerve Sheath Tumors in NF1
A study finds that in characterization of peripheral nerve sheath tumors as benign or malignant in patients with neurofibromatosis type 1, MRI-obtained apparent diffusion coefficient and FDG-PET/CT-obtained maximum standardized uptake values are excellent imaging markers.
Should Aging Physicians Be Required to Undergo Cognitive Testing?
The issue of aging physicians poses serious challenges to the medical profession, with concerns that judgment or skills might decline with age.
Purdue Files for Bankruptcy Over Opioid Crisis Suits
OxyContin maker Purdue Pharma has filed for Chapter 11 bankruptcy, touching off what could be a fierce battle by dozens of states hoping to recoup billions spent fighting the opioid crisis.
Imaging Technique Specific in Differentiating MS From Other Diseases
Central vein sign at 3T ultrahigh-field magnetic resonance imaging is highly specific and moderately sensitive in the differentiation of multiple sclerosis from other diseases.
Bullying During Medical Residency May Cause Depression, Burnout
Researchers evaluated survey results to determine the prevalence and impact of perceived bullying during residency.
Increased Spending Found With Treatment at Hospital-Owned Practices
Financial integration between physicians and hospitals raises patient spending but does not impact care quality.
The Clinical Presentation of NF2 During the First Decade of Life
As most young children with neurofibromatosis type 2 (NF2) do not initially present with vestibular schwannomas, it is important to consider this diagnosis in children with the characteristic ocular abnormalities or a meningioma, according to the largest series of young pediatric patients with NF2.
Imaging Technique May Help Predict Stroke-Related Dementia
Diffusion tensor image segmentation technique, which characterizes microstructural damage across the cerebellum, identifies damage in cerebral small vessel disease and can predict dementia.
Mild Cognitive Impairment Incidence Higher Among WTC First Responders
The incidence of mild cognitive impairment (MCI) is increased in World Trade Center responders.
Integrated Care May Improve Migraine and Chronic Tension-Type Headache
Researchers analyzed the efficacy of interdisciplinary multimodal integrated care in patients with chronic migraine and/or tension-type headache.
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