Alzheimer Disease and Dementia

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The Association Between Sleep and Brain Morphology in Mild Cognitive Impairment

In patients with mild cognitive impairment, sleep habits are associated with gray matter atrophy and alterations in functional connectivity.

Anosognosia May Serve as an Early Indicator of Alzheimer Disease

This study looks at how the lack of awareness (anosognosia) of memory impairment evolves in the trajectory of Alzheimer disease.

Actigraphy Sleep Patterns Predict Cognitive Changes, Middle-Aged Hispanic/Latino Population

Longer sleep-onset latency, as monitored by wrist actigraphy, predicts long-term declines in global cognitive function, verbal learning, and memory in Hispanic/Latino adults.

Late-Onset Epilepsy Associated With Increased Risk for Subsequent Stroke

This systematic review identified studies related to late-onset epilepsy (LOE) to investigate the association between LOE and subsequent stroke and Alzheimer dementia.

Patients With Both Dementia and Severe Mental Illness Experience Faster Cognitive Decline

Researchers analyzed data from the population of 4 South London boroughs to determine the impact of comorbid bipolar disorder and schizophrenia on the cognitive decline in dementia.

In Older Adults with Cognitive Impairment, Amyloid-β (Aβ) Deposition May Be Linked to Air Pollution

Amyloid-β (Aβ) deposition, a feature of Alzheimer disease, may be promoted by external factors. The researchers of this study examined the association between the likelihood of amyloid positron emission tomography (PET) scan positivity and ambient air quality in individuals with cognitive impairment.

Disparities Persist in Dementia Risk of Black and White Adults

Researchers analyzed data from a nationally representative study of older non-Hispanic Black and White adults to evaluate progress toward reducing racial disparities regarding dementia.

Therapies Which Enhance PLCG2 Activity May Be Effective in Treating Parkinson and Alzheimer Diseases

The study authors sought to determine which components of the peripheral immune response correlated with diagnoses of Alzheimer or Parkinson Disease.

The Bi-Directional Association Between Dementia and Epilepsy

Dementia and epilepsy have a bi-directional relationship as either condition has approximately a 2-fold probability of developing the other.

Pre-Existing Alzheimers And Dementia Associated With Risk of Hospitalization Of COVID-19

Researchers found in an observational cohort study that pre-existing Alzheimer disease and dementia are top risk factors for severe COVID-19 based on their association with positive tests for the coronavirus in England’s hospitals in spring 2020.