Alzheimer Disease and Dementia

Latest News

Researchers Propose New Definition of Brain Health

In correspondence published in The Lancet Neurology, researchers proposed a new definition of adult brain health.

Intracerebral Hemorrhage Linked to Increased Risk of Cognitive Decline at Young Age

This was a retrospective cohort study that compared the risk of dementia in young patients with traumatic compared with spontaneous intracerebral hemorrhage.

Nelotanserin May Be Ineffective for Motor, Vocal Manifestations of RBD in Lewy Body and PD Dementia

Using systematic video analysis, researchers assessed the efficacy of nelotanserin for symptomatic treatment of REM sleep behavior disorder in patients with dementia.

Gene Therapy Fast Tracked for APOE4 Associated Alzheimer Disease

The investigational adeno-associated virus mediated gene therapy is being developed to deliver the protective APOE2 gene to the CNS.

Case Study: Amyloid-PET Positive Patient With Frontotemporal Behavioral Dementia

Researchers evaluated a case study of a patient who was diagnosed with frontotemporal behavioral dementia whose autopsy showed coexistent TDP-43 type A and Alzheimer disease pathologies and cerebrovascular disease.

Comprehensive Diagnostic Services and Timely Diagnosis of Dementia Vary on the Basis of Ethnicity and Sociodemographic Characteristics

The study authors sought to examine the associations between race/ethnicity and timeliness of dementia diagnosis, as well as the comprehensiveness of diagnostic evaluation.

Prostate Cancer Hormone Therapy Tied to Dementia, Depression in Younger Men

Findings from a recent study emphasize the importance of neurocognitive assessment in men undergoing ADT, especially in younger patients, according to investigators.

History of Psychiatric Disease Inversely Correlates with Age of Onset in Alzheimer’s Disease

There may be an association between a history of psychiatric disorders in patients and age of onset of Alzheimer disease.

Progression of β-Amyloid Deposition and Consequences on Cognitive Impairment

Evidence suggests the importance of decreasing -amyloid deposition in brains of patients with Alzheimer disease early in care.

Lewy Body Dementia With AD Copathology Linked to Impaired Language Performance

Patients with Lewy body dementia with likely AD-type copathology may have impaired language compared to those without such copathology.