Alzheimer Disease and Dementia

ALZHEIMER’S DISEASE & DEMENTIA

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Program Offers Rapid Genetic Test for Spinal Muscular Atrophy at No Charge

A new rapid turnaround genetic test for spinal muscular atrophy, found to reduce time to results from 21 days to 4 days, will be offered at no charge to qualified individuals in the United States as part of the SMA Identified program.

Higher levels of alcohol and tobacco use put men at risk for liver disease, such as cirrhosis and alcoholic liver disease. Men who have sex with men are at increased risk for viral hepatitis B, and should be screened accordingly.

Trial Investigating Treatment for Hyperammonemia in Cirrhosis Discontinued

Synologic, Inc announced that following disappointing top-line data from a phase 1b/2a study, the Company will discontinue the development of SYNB1020 for the treatment of hyperammonemia.

Evidence Supports Use of Medications for Pain Relief in Pediatric Migraine

Evidence-based therapies are available for the acute symptomatic treatment of migraine in children and adolescents, but evidence is lacking for the impact of many treatments for migraine prevention.

OnabotulinumtoxinA Injection of Sphenopalatine Ganglion May Not Improve Trigeminal Neuralgia

The injection of onabotulinumtoxinA toward the sphenopalatine ganglion in patients with trigeminal neuralgia may not reduce the number of attacks.

FDA Approves Pitolisant for Excessive Daytime Sleepiness in Adults With Narcolepsy

Wakix is a selective H3 receptor antagonist/inverse agonist and the first treatment for narcolepsy that is not scheduled as a controlled substance.

Risk Factors for Tardive Dyskinesia in Patients Taking Antipsychotics

The risk factors for tardive dyskinesia in patients taking antipsychotics include age, comorbid diagnoses, and high medication dosages.

Traumatic Brain Injury May Increase Risk for Suicide Among Veterans

Veterans diagnosed with a traumatic brain injury (TBI) are at a higher risk for suicide in comparison with those without a TBI diagnosis, especially when the severity is moderate to severe.

Remote Electrical Neuromodulation Noninferior to Usual Care for Acute Migraine

Remote electrical neuromodulation may represent a safe and effective option for the acute treatment of migraine.

FDA Rejects Supplemental New Drug Application for Tasimelteon in Jet Lag Disorder

The FDA has rejected the supplemental New Drug Application for Hetlioz (tasimelteon; Vanda Pharmaceuticals) for the treatment of jet lag disorder.

The mechanisms that drive this benefit are not well-understood, and it is believed that the benefit

Physical Activity Influences Migraine Risk in Men and Women

Canadian researchers found data that showed social determinants of health are linked to migraine prevalence across sexes.

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