Brain Tumors

Latest Articles

Outcomes Poor Years After Radiation for Pediatric Glioma Survivors

Survivors of childhood low-grade gliomas treated with radiotherapy have poorer neuropsychological and socioeconomic-status outcomes.

Computer-Assisted Diagnosis Aids Detection of Glioma Growth

Computer-assisted diagnosis (CAD) can help physicians detect growth of low-grade gliomas.

Phase 3 Study of Investigative Glioblastoma Treatment Halted

AbbVie has halted enrollment in all ongoing studies of depatuxizumab mafodotin, after an Independent Data Monitoring Committee (IDMC) recommended a phase 3 study of the treatment be stopped due to a lack of survival benefit.

Lifetime Risk for Brain Metastasis Increased in Elderly With Some Common Cancers

Highest incidence seen for patients with non-small cell lung cancer and triple-negative breast cancer

Contrast-Enhanced MRI Characterization of Brain Cancers

According to researchers, neovascularization is more common in glioblastoma, and extravasation is more common in primary CNS lymphoma.

Combining CAR-T and BiTE in Models of Glioblastoma Multiforme

This study involved the engineering of CAR-T cells specific for the EGFRvIII antigen to also secrete bispecific T cell engagers (BiTEs) against wild-type EGFR.

Neoadjuvant PD-1 Blockade Seems Effective in Glioblastoma

Neoadjuvant administration of programmed cell death protein 1 (PD-1) blockade seems to enhance local and systemic antitumor immune response in glioblastoma.

Statins, NSAIDS Have No Apparent Survival Benefit for Grade IV Glioma

In certain parts of the analysis, the use of selective COX-2 inhibitors and metamizol was associated with inferior patient survival.

Novel Glioblastoma Treatment Granted Orphan Drug Designation

In preclinical models, the inhibition of phosphorylated STAT3 (p-STAT3) by WP1066 resulted in the direct attack of various tumor cells.

Sex Differences ID’d in Response to Glioblastoma Treatment

Standard therapy is more effective for female vs male patients with glioblastoma.