Salicylate NSAIDs Slow Growth of Vestibular Schwannomas

In a previous study, the researchers found aspirin to be beneficial in preventing proliferation of the cells.

Researchers from Massachusetts Eye and Ear and the Harvard Medical School/ Massachusetts Institute of Technology’s Program in Speech and Hearing Bioscience and Technology have demonstrated that salicylates, a class of non-steroidal inflammatory drugs (NSAIDs), reduced the proliferation and viability of cultured vestibular schwannoma cells that cause a sometimes lethal intracranial tumor that typically causes hearing loss and tinnitus.

The research is described in “Non-steroidal Anti-inflammatory Medications are Cytostatic Against Human Vestibular Schwannomas” online in Translational Research.

Vestibular schwannomas are the most common tumors of the cerebellopontine angle and the fourth most common intracranial tumors.

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