Seizure Disorders

Latest News

Complex Neurocognitive Skills Delayed in Youth With SCN8A Variant Epilepsy

In the first study of this size, researchers found complex neurocognitive skills, typically acquired later in development, are the most delayed skills in youth with SCN8A‐related epilepsy.

Single-Dose Midazolam Nasal Spray Demonstrates High Seizure Termination in Patients With Seizure Clusters

Intermittent and repeated exposure to midazolam administered as a single‐dose nasal spray was generally well tolerated and effective for terminating seizures within 10 minutes in a large proportion of patients who experienced seizure clusters.

FDA Reports More Seizures Among E-Cigarette Users

There have been 118 more reports of electronic cigarette users suffering seizures since the FDA first warned the public about the danger in April, bringing the total number of reported cases to 127 between 2010 and 2019.

Dravet Syndrome: Therapy Targeting Underlying Cause Gets Orphan Drug Status

The Food and Drug Administration has granted Orphan Drug designation to STK-001 (Stoke Therapeutics) for the treatment of Dravet syndrome.

Focal Epilepsy Associated With Acceleration in Progressive Cortical Thinning

Focal epilepsy may accelerate widespread progressive cortical thinning to a greater degree than that observed in normal aging.

Aging May Reduce Risk for New-Onset Epilepsy and Refractory Epilepsy Following Stroke

Epilepsy and refractory epilepsy is less likely to be associated with stroke in older adult survivors and more likely to be associated with younger age and other factors.

Multiple Sclerosis Increases Risk for Seizures and Epileptic Activity

Patients with MS and comorbid seizures or epilepsy presenting to a neurology department in at one hospital in Germany between 2003 and 2015 were identified.

FDA to Review Liquid Formulation of Lamotrigine

The FDA has accepted for review a New Drug Application for ET-105, a new liquid formulation of lamotrigine.

Prenatal Antiepileptic Drug Exposure Associated With Increased Childhood Behavioral Problems

A study found a higher percentage of parental reports of behavioral problems in children of mothers with epilepsy prenatally exposed to antiepileptic drug monotherapy.

Migraine Comorbidity in New Focal Epilepsy Not Associated With Cognitive Impairment

Among those with new onset focal epilepsy, migraine comorbidity has shown no correlation with objective cognitive scores.