Epilepsy Headlines

LATEST

Air Pollution as a Potential Risk Factor for Epileptic Seizures

Researchers sought to examine the relationship between air pollution exposure and the occurrence of epileptic seizures.

Gait, Motor Function Gradually Worsened in Adults With Dravet Syndrome

In a prospective, cross-sectional study, researchers assessed gait and motor disturbances among adult patients with Dravet syndrome.

Is Breastfeeding Safe for Infants of Women With Epilepsy on Antiseizure Medication?

In a systematic review, researchers reported on the presence of antiseizure medications in the breast milk of women with epilepsy and potential infant exposure to those who were breastfed.

VNS May Cut Hospital Costs for Children With Refractory Epilepsy

Antiseizure medication (ASM) plus vagus nerve stimulation (VNS) is associated with lower annual hospital costs over time for pediatric patients with refractory epilepsy compared to ASM alone.

Long-Term Outcomes of Patients With Transient Epileptic Amnesia

Researchers sought to evaluate the long-term outcomes of transient epileptic amnesia in relation to seizure control, memory, medical comorbidities, and life expectancy.

Posttraumatic Epilepsy More Likely to Be Drug Resistant

Individuals with posttraumatic epilepsy (PTE) are more likely to have drug-resistant epilepsy (DRE), and they report lower quality of life.

Oral Perampanel Well Tolerated in Pediatric Epilepsy

Daily oral perampanel is generally well tolerated, with favorable retention rates among patients with epilepsy aged 1 to younger than 18 years.

EEG, Seizure Type Combinations Predict Antiseizure Medication Resistance

In a case-control study, researchers compared clinical and EEG characteristics between patients with antiseizure medication (ASM)-resistant idiopathic generalized epilepsy (IGE) and ASM-responsive IGE.

Ganaxolone: A Treatment for Major Motor Seizures in CDKL5 Deficiency Disorder

In a global, phase 3 trial, researchers evaluated the efficacy of ganaxolone as an adjunctive treatment compared to placebo for major motor seizures in patients with CDKL5 deficiency disorder.

Epilepsy, Hearing Loss As Early Signs of Parkinson Disease Among Diverse Patients

Researchers sought to examine the link between risk factors and early presentations of PD in an ethnically diverse population living in areas of high social deprivation but with access to universal health care in the UK.

Understanding Psychogenic Nonepileptic Seizures: Diagnosis to Treatment

Nitin K. Sethi, MD, MBBS, and Gaston C. Baslet, MD, discuss the importance of distinguishing psychogenic nonepileptic seizures (PNES) from epilepsy and the challenges of managing PNES.

Early Seizures Following Traumatic Brain Injury Tied to Poor Outcomes

Researchers sought to identify early posttraumatic seizure (EPS) risk factors, evaluate the morbidity and mortality involved with EPS, and develop a risk assessment prediction model for EPS.

Coma After Cardiac Arrest: Should Rhythmic and Periodic EEG Activity Be Treated?

Researchers sought to evaluate whether the use of intensive, stepwise antiseizure therapy and sedative treatment to suppress rhythmic and periodic EEG patterns detected with the use of continuous EEG monitoring would improve outcomes among patients in a comatose state following cardiac arrest.

Early Posttraumatic Seizures Tied to Worse Traumatic Brain Injury Outcomes

Early posttraumatic seizures (EPS) after moderate-to-severe traumatic brain injury (TBI) are associated with poor outcomes.

Concentrations of Certain Antiseizure Meds Drop During Pregnancy

Among pregnant women with epilepsy, dose-normalized concentrations of several antiseizure medications decrease during pregnancy.

Therapeutic Monitoring of Antiseizure Drugs Should Begin Early in Pregnancy

Researchers sought to describe pregnancy-related blood concentration changes in a number of antiseizure medications used among women with epilepsy.

Responsive Neurostimulation Tolerated in Pediatric Epilepsy

Responsive neurostimulation (RNS; NeuroPace) is tolerated and may be effective in carefully selected pediatric epilepsy patients.

Genetic Diagnosis May Aid Management of Pediatric Epilepsy

For individuals with unexplained infantile or childhood-onset epilepsy, genetic testing to establish a genetic diagnosis may impact medical care and prognosis.

Natalizumab Shows Weak Impact in Patients With Drug-Resistant Epilepsy

In a phase 2 trial, researchers assessed the safety and efficacy of natalizumab as adjunctive therapy in adults with drug-resistant epilepsy.

Delay to Diagnosis of Nonmotor Seizures Longer in Youth

Although many individuals with focal epilepsy experience delays to diagnosis, children and teens with this disorder face even longer delays than adults.