Certain patients with Lennox-Gastaut syndrome (LGS) may be good candidates for curative epilepsy surgery, emerging research suggests.

A new case series shows that two thirds of patients with LGS were seizure-free or markedly improved following resective surgery.

“Most patients with LGS are not candidates for curative surgery, but there is a small subset, especially the ones with an MRI abnormality, and especially those with an abnormality on one side of the brain, who may be candidates,” Ahsan Moosa Naduvil, MD, Section of Pediatric Epilepsy, Cleveland Clinic Epilepsy Center, Ohio, told Medscape Medical News.

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