Marijuana, Nicotine Use Affects Brain Structure, Memory Processing

Combined use of marijuana (MJ) and tobacco is highly prevalent in today’s population. Individual use of either substance is linked to structural brain changes and altered cognitive function, especially with consistent reports of hippocampal volume deficits and poorer memory performance. 

However, the combined effects of MJ and tobacco on hippocampal structure and on learning and memory processes remain unknown. In this study, we examined both the individual and combined effects of MJ and tobacco on hippocampal volumes and memory performance in four groups of adults taken from two larger studies.

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