The use of triptans is contraindicated in patients with migraine and a history of ischemic stroke or coronary artery disease, although there’s no substantial evidence that they directly increase the risk for vascular events.
In a double-blind, placebo-controlled, randomized study, researchers sought to determine the exact site of interaction between the occipital and trigeminal nerves and the mechanisms of this interaction.
In a randomized, placebo-controlled crossover study, researchers determined the effect of a 2-hour vasoactive intestinal polypeptide infusion on risk for migraine attacks.
