This study addresses the controversy about the efficacy of currently used treatment modalities to alleviate acute migraine headaches.

Ali Shahrami, MD, of Shahid Beheshti University of Medical Sciences in Tehran, Iran, and colleagues, compared the effects of two common migraine treatments, magnesium sulfate and dexamethasone/metoclopramide, on patients suffering from acute migraine headache. 70 patients were split into two equal treatment groups, evaluating pain at baseline. The researchers found that magnesium sulfate was a faster-acting and more effective treatment than dexamethasone/metoclopramide for migraine.

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