Several reports describe a possible association between restless legs syndrome and Parkinson disease, as well as Tourette syndrome and restless legs syndrome.
Valbenazine and tetrabenazine may represent promising options for the treatment of tardive dyskinesia in patients on long-term antipsychotic medications.
Combined single inhaled doses of CVT-301 and oral carbidopa/levodopa therapy taken during early morning OFF symptoms demonstrated tolerability and lack of serious adverse events.
The risk for Parkinson disease is increased after appendectomy.
HealthDay News — Isradipine does not appear to slow progression of disability in patients with de novo Parkinson disease (PD), according to a study presented at the annual meeting of the American Academy of Neurology, held from May 4 to 10 in Philadelphia. Tanya Simuni, MD, from the Northwestern University Feinberg School of Medicine in…
Use of zonisamide showed long-term efficacy for Parkinsonism and dementia with Lewy bodies without deterioration of cognitive function.
Carbidopa/levodopa enteral suspension leads to improvement in quality of like and activities of daily living measures in patients with advanced Parkinson disease.
Antisense oligonucleotide drug HTTRx reduced the concentration of mutant huntingtin protein in the cerebrospinal fluid of persons with Huntington disease.
There were no significant differences between pimavanserin and quetiapine in time to discontinuation, mortality, or improvement in psychosis in patients with Parkinson disease and Lewy body dementia.
Extension study showed that levodopa inhalation powder maintained its efficacy in achieving an ON state in patients with Parkinson disease experiencing OFF periods.