In this case study, Camila C. Aquino, MD, MSc, of the Morton and Gloria Shulman Movement Disorders Center at Toronto Western Hospital in Ontario, Canada, and colleagues observed a female Parkinson’s disease patient complaining of severe and disabling symptoms in the genital region, including burning sensations, tingling and pain. Previous rare cases were attributed to nonmotor off symptoms.

While restless genital syndrome is rare, researchers suggest that it be included in the differential diagnosis of genital symptoms and restlessness, and recommend treatment with a dopamine agonist. 

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