Abstract Background: Despite an urgent need for new medications, clinical trials in Parkinson’s have a relatively low rate of success. Although many reasons have been proposed for this, the opinions of patients and scientists, the two principal stakeholders, have not been widely canvassed. Objective: The objective of the present study was to establish the main barriers to clinical trials success in Parkinson’s, as perceived by people with Parkinson’s and those engaged in conducting clinical trials in Parkinson’s. Method: Three hundred and three people (303) with a connection to Parkinson’s completed an online four-item questionnaire, directed towards discovering the barriers that interfere with the establishment of effective clinical trials. 

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