Recognizing the Early Signs of Relapsing-Remitting MS Progression
A combination of clinical, imaging, and neuropsychological examinations may aid in MS disease progression prognostication.
Multiple Sclerosis
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Patients With Neuromyelitis Optica at Increased Risk for Fracture
Given the limited data is available on bone health of patients with NMOSD-AQP4, researchers aimed to investigate their risk for fracture and bone loss.
Study Characterizes Treatment and Prognostic Factors Associated With MS Related Trigeminal Neuralgia
Researchers sought to collect information on the characteristics of MS-related TN and on the frequency and type of medical/surgical treatments.
Low Vitamin D, Smoking Predict Worse Cognitive Function in MS
The researchers found that higher vitamin D predicted better cognitive performance, while smoking predicted worse performance.
Monomethyl Fumarate Gets Final FDA Approval for Multiple Sclerosis
The FDA has granted final approval to Bafiertam™ (monomethyl fumarate; Banner Life Sciences) for the treatment of relapsing forms of multiple sclerosis.
Siponimod Continues to Benefit in Secondary Progressive MS, According to Long-Term Data
New data from the 5-year EXPAND open-label extension trial evaluating siponimod in patients with SPMS showed that the treatment slowed physical disability progression and provided cognitive benefits.
Oral Ponesimod Compared to Teriflunomide for Relapsing Multiple Sclerosis
In patients with relapsing MS ponesimod was found to be superior to teriflunomide on annualized relapse rate, MRI activity and brain atrophy.
Comparing Moderate vs High Efficacy DMT After Natalizumab Discontinuation for MS
Switching from natalizumab to moderate DMT vs switching to high efficacy therapy in MS patients was associated with lower rates of no disease activity.
FDA to Review Data on Shorter Infusion Time for Ocrelizumab
The FDA has accepted for review the supplemental Biologics License Application (sBLA) for a 2-hour Ocrevus (ocrelizumab; Genentech) infusion time, shortening the conventional infusion duration for patients with relapsing or primary progressive multiple sclerosis (MS).
The Relationship Between Gut Microbiota and Neurodegenerative Disorders
The microbiota-gut-brain axis represents a bidirectional communication pathway through which the gut microbiota may influence the CNS.
Early White Matter Changes Noted in Youth With Genetic Predisposition for MS
Greater genetic predisposition for MS tied to imaging-observable changes in white matter in preteens
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