A Personal Decision
Ultimately, the patient and physician must decide mutually on the most appropriate treatment option and acceptable level of risk of PML. Patients with high disease activity and multiple indicators of poor prognosis, for example, may decide that a higher level of efficacy is worth an increased risk.
Meanwhile, research continues to work towards facilitation of more precise personalization of treatment. Using data from the MSBase registry, Dr Kalincik and colleagues have been investigating the topic of individually tailored therapy, and they believe they “will soon be able to provide clinicians and their patients with some valuable supportive information concerning individual treatment choice,” he said.
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