Responses to treatment depend on the target chosen, with 5 targets yielding positive outcomes, including the ventral anterior limb of the internal capsule, subthalamic nucleus, nucleus accumbens, ventral capsule/ventral striatum, or inferior thalamic peduncle, all involving fronto-striato-thalamocortical circuits.
Results showed a mean change from baseline of -9.28 points (95% CI, -10.23 to -8.32) on the HAM-A total score in patients treated with troriluzole compared with -9.35 points (95% CI, -10.34 to -8.36) with placebo (P =.917).
Depression, anxiety, and reduced quality of life are seen more frequently in patients with atopic eczema—and these associations imply that it may be more than just a skin disease.
The results of the study point to the validity of the Research Domain Criteria initiative and suggest that neuroimaging findings may not be specific to certain psychiatric disorders.
Compared with patients without PTSD, patients with both bipolar disorder and PTSD were more likely to be women, on disability, have a lower education level, and have a lower annual household income.
Researchers examined the association between neuropsychiatric events and health-related quality of life in a cohort of patients with systemic lupus erythematosus.
The relationship between eczema phenotypes and school-age emotional and behavioral problems, as well as the bidirectional relationship between eczema and emotional and behavioral problems in children between birth and age 10 years, was analyzed in this study.
The study provides strong evidence for the utility of resting-state fMRI measures in predicting the development of attentional or mood disorders in children.
Akili Interactive announced topline data from an open-label study (STARS-ADHD Adjunctive) of AKL-T01 for the treatment of attention deficit hyperactivity disorder in children with or without use of stimulants.
