Delirium is highly prevalent in critical care, especially among elderly patients and individuals with dementia. Although rates vary widely across studies, findings suggest delirium affects more than 15% of hospitalized patients. For additional discussion regarding this topic, Neurology Advisor interviewed Leopoldo Pozuelo, MD, MBA, FACP, FACLP, clinical vice chair of psychiatry and psychology at the Cleveland Clinic in Ohio.
The USPSTF concludes that the evidence is currently inadequate for weighing the benefits and harms of screening for cognitive impairment among older adults.
Current evidence does not support routine use of haloperidol or second-generation antipsychotics for prevention or treatment of delirium in hospitalized adults.
Investigators studied the effects of midlife high or increasing blood pressure on late-life brain structure.
Treatment with methylphenidate (MPH) affects specific tracts in brain white matter in boys with attention-deficit/hyperactivity disorder.
Variation in autism spectrum disorder occurrence may be due to genetic influences, rather than maternal or environmental effects.
Middle-aged women, but not men, with a greater number of recent stressful life events have memory decline later in life.
The prevalence of cognitive impairment is higher in patients with COPD compared with healthy individuals.
Two pivotal phase 2/3 studies investigating umibecestat (CNP520) for the prevention of Alzheimer disease have been discontinued due to worsening in some measures of cognitive function.
Estradiol has anti-inflammatory properties and can strengthen the hypothalamic-pituitary-adrenal axis, which may oppose the effects of visceral adiposity.