Endocrine events that signal less exposure to estradiol, such as shorter reproductive span, younger age at menopause, and hysterectomy, increase dementia risk.
Investigators sought to establish the effect of hyperglycemia and metformin use on relevant B-vitamin biomarkers and cognitive outcomes in older adults.
Computerized cognitive training significantly improved global cognitive function in patients with subcortical vascular cognitive impairment.
Elderly individuals treated with antihypertensive medications and have a SBP of ≥130 mm Hg display less cognitive decline after 1 year compared with individuals with an SBP of <130 mm Hg.
Researchers suggest that improvement in cognitive function should be a goal for major depressive disorder because their data showed little improvement in the cognitive abilities of patients with major depression after treatment with psychological interventions.
No association was found between the long-term influence of pregnancy history and age-related changes in cognitive function.
Higher Mediterranean diet (MedDiet) and A Priori Diet Quality Score (APDQS) scores are associated with better cognitive performance in midlife.
Blood pressure and lipid lowering medications do not reduce cognitive decline.
Candesartan plus hydrochlorothiazide, rosuvastatin, or their combination do not impact cognitive decline among older people.
Midlife systemic inflammation is associated with cognitive decline.