HealthDay News — Delirium appears to predict reduced functioning in elderly individuals after surgical aortic valve replacement (SAVR) or transcatheter aortic valve implantation (TAVI), according to a study published in the Journal of the American Geriatrics Society.

Leslie S.P. Eide, from the University of Bergen in Norway, and colleagues assessed 136 individuals aged 80 years and older undergoing elective SAVR or TAVI. The Confusion Assessment Method was used to assess delirium for 5 days.

The researchers found that at 1 month post-SAVR, participants had lower instrumental activity of daily living (IADL) scores than at baseline (P ≤ 0.02), but scores returned to baseline levels at 6 months. At 6-month follow-up, the Medical Outcomes Study 12-item Short-Form Health Survey (SF-12) Physical Component Summary score was higher than at baseline, particularly in participants who did not develop delirium (P < 0.001). Regression models showed that delirium may predict IADL disability at 1-month follow-up (P ≤ 0.07) but does not predict large differences in ADL disability, cognitive function, or SF-12 scores. Greater ADL and IADL disability at 1-month, but not at 6-month, follow-up was predicted by delirium after TAVI.

“Individuals who develop delirium after SAVR and TAVI have poorer short-term IADL function but do not seem to have long-term reductions in physical, mental, or self-reported health,” the authors write.


Eide LS, Ranhoff AH, Fridlund B, et al. Delirium as a Predictor of Physical and Cognitive Function in Individuals Aged 80 and Older After Transcatheter Aortic Valve Implantation or Surgical Aortic Valve Replacement. J Am Geriatr Soc. 2016; doi:10.1111/jgs.14165.