In patients with Huntington disease, higher levels of functional impairment and current alcohol consumption were significantly correlated with missing work in multivariate logistic regression analyses.
The presence of P-tau181 may aid in the diagnosis and identification of prognostic outcomes in Alzheimer disease.
Patients with Parkinson disease tend to have an increase in iron content with reduced perfusion in the substantia nigra.
A simple SVD score using MRI scans, may aid in identifying patients with SVD who are likely to develop cognitive decline.
The Food and Drug Administration has granted Fast Track designation to verdiperstat (BVH-3241; Biohaven) for the treatment of multiple system atrophy.
Emotions, cognitions, and behaviors are significantly associated with pain severity and pain-related interference in IBD, including pain-specific cognitions and behaviors.
Up to half of patients with Parkinson disease are also diagnosed with dementia, but tools to track changes in cognition are lacking.
Bladder training and conservative advice may improve lower urinary tract symptoms in patients with Parkinson disease.
There is a distinct genetic signature for young-onset Parkinson disease even in cells from those who have no known Parkinson disease-related mutations.
Serum NfL levels are indicative of ongoing neuroinflammation and may be predictive of neurodegeneration in patients with early MS.