Older adults with an increase in amyloid-β plaques followed by increased tau neurofibrillary tangles have shown lower cognition after 7 years.
Study showed an association between early-onset Alzheimer disease and higher levels of low-density lipoprotein cholesterol independent of the effects of APOE, as well as demonstrated enrichment of rare coding variants of APOB.
An entorhinal cortex-based virtual reality navigation task can differentiate patients with mild cognitive impairment at low and high risk for developing dementia.
Prospective population-based study explores relationship between serum urate concentration and risk for dementia.
The total tau concentration measured in either CSF or blood is strongly associated with survival time in sporadic Creutzfeldt-Jakob disease.
A number of psychiatric and neurodegenerative diseases are associated with abnormal imaging findings, which can help psychiatrists reach a diagnosis.
A study describes early lesion development in asymptomatic boys with childhood cerebral ALD.
No significant difference in outcomes was observed in children and adolescents with fragile X syndrome (FXS) receiving adaptive versus nonadaptive in-home cognitive training.
Results indicated a considerably higher prevalence of carriers of intermediate and pathological ranges of polyglutamine disease–associated alleles among the general population than previously estimated.
For people with ALS, African-Americans have longer survival than Caucasians when death is the outcome, but not when the outcome is death or tracheostomy and invasive ventilation.