In research settings, including patients with neurodegenerative diseases presents challenges regarding consent, communication, and ability to participate that must be addressed in order to avoid evidence-biased care.
In a nationwide register-based cohort study, researchers assessed the prevalence and incidence of Parkinson disease among patients screened for diabetic retinopathy.
In a prospective natural history study, researchers tested the association between body mass index and height and clinical characteristics in Friedreich ataxia.
Elivaldogene autotemcel (eli-cel) is a one-time gene therapy designed to add functional copies of the ABCD1 gene into a patient’s own hematopoietic stem cells, resulting in the production of ALDP.
For patients with Parkinson disease on levodopa therapy, patient-rated quality of life is similar for those receiving adjuvant therapy with dopamine agonists compared with dopamine reuptake inhibitors.
For individuals who have conversion of MCI to dementia, statistically significant decreases in cognitive test scores occur at least six months earlier with the SAGE than with the non-self-administered MMSE.
Researchers sought to investigate the association between lower retinal nerve fiber layer thickness, a marker of neurodegeneration, with clinically relevant depressive symptoms and depressive symptoms over time.
