Neurodegenerative Diseases

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Vitamins E, C Inversely Linked to Risk for Parkinson Disease

Dietary vitamin E and vitamin C intake may be inversely associated with Parkinson disease risk.

Actigraphy Sleep Patterns Predict Cognitive Changes, Middle-Aged Hispanic/Latino Population

Longer sleep-onset latency, as monitored by wrist actigraphy, predicts long-term declines in global cognitive function, verbal learning, and memory in Hispanic/Latino adults.

Late-Onset Epilepsy Associated With Increased Risk for Subsequent Stroke

This systematic review identified studies related to late-onset epilepsy (LOE) to investigate the association between LOE and subsequent stroke and Alzheimer dementia.

Sleep Quality and Cognitive Function in Patients With Mild Traumatic Brain Injury

Researchers compared sleep quality and biomarkers of neurodegeneration and cognitive scores between so-called poor sleepers and good sleepers with mild traumatic brain injury.

In Older Adults with Cognitive Impairment, Amyloid-β (Aβ) Deposition May Be Linked to Air Pollution

Amyloid-β (Aβ) deposition, a feature of Alzheimer disease, may be promoted by external factors. The researchers of this study examined the association between the likelihood of amyloid positron emission tomography (PET) scan positivity and ambient air quality in individuals with cognitive impairment.

Disparities Persist in Dementia Risk of Black and White Adults

Researchers analyzed data from a nationally representative study of older non-Hispanic Black and White adults to evaluate progress toward reducing racial disparities regarding dementia.

Therapies Which Enhance PLCG2 Activity May Be Effective in Treating Parkinson and Alzheimer Diseases

The study authors sought to determine which components of the peripheral immune response correlated with diagnoses of Alzheimer or Parkinson Disease.

Pre-Existing Alzheimers And Dementia Associated With Risk of Hospitalization Of COVID-19

Researchers found in an observational cohort study that pre-existing Alzheimer disease and dementia are top risk factors for severe COVID-19 based on their association with positive tests for the coronavirus in England’s hospitals in spring 2020.

Researchers Explore Gene Regulatory Pathways and Neurological Disease

Study results provide new insight into how neuron subtypes outside the substantia nigra pars compacta may be compensating at a molecular level for differences in the motor production neural circuit during the progression of Parkinson’s disease.

The Glymphatic System: Importance of Sleep for Clearance of Brain Protein Waste

Degradation of the glymphatic system over time due to age and sleep disturbance may be associated with neurodegenerative dementias.