Neurodegenerative Diseases

Latest News

Cerebrovascular Reactivity Predicts Cognitive Impairment Independent of AD

MRI-based cerebrovascular reactivity is associated with cognitive function independent of Alzheimer disease pathology.

Aducanumab Gets Priority Review for Alzheimer Disease

The FDA has accepted for Priority Review the Biologics License Application for aducanumab for the treatment of Alzheimer disease.

Oral Therapy Evrysdi Approved for Spinal Muscular Atrophy

Evrysdi is a survival motor neuron-2 (SMN2) splicing modifier.

The Lancet Commission Identifies Additional Dementia Risk Factors

The Lancet Commission added 3 new risk factors for dementia that coupled with the previous 9 lifestyle risk factors might prevent or delay up to 40% of dementias worldwide.

Education May Affect β-Amyloid Burden in Alzheimer Disease

Years of education and the ε4 risk allele at APOE influence β-amyloid pathology in asymptomatic individuals with a parental history of sporadic AD, while only years of education influence β-amyloid pathology in presymptomatic autosomal dominant AD mutation carriers.

P-tau217 Shows Promise as Biomarker for Alzheimer Disease

Plasma tau phosphorylated at threonine 217 (P-tau217) shows promise as a biomarker for Alzheimer disease (AD).

Dual Sensory Impairment Ups Dementia Risk

Older adults with both hearing and visual impairments – dual sensory impairment – are at a significantly increased risk for dementia.

Poor Dental Health May Increase Risk for Incident Dementia, MCI

Individuals with severe periodontal disease or edentulism have an increased risk for incident dementia.

Frontal Lobe Cognitive Dysfunction Symptom Reduction Associated With Rotigotine Therapy

Researchers conducted a randomized clinical trial to assess whether 24 weeks of treatment with rotigotine can modify cognitive functions in patients with mild to moderate Alzheimer disease.

Worse Multisensory Function May Accelerate Cognitive Aging

Faster rates of cognitive decline were seen in association with each point worse in the multisensory function score.