Neurodegenerative Diseases

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Assessing the Overlapping Brain Pathologies in Obstructive Sleep Apnea, Alzheimer Disease

Researchers analyzed autopsy brain tissue from confirmed obstructive sleep apnea cases for amyloid beta and tau, hallmark proteins of Alzheimer disease.

Catheter Ablation for A-Fib Linked to Reduced Dementia Risk

Catheter ablation is associated with reduced dementia risk compared with medical management in patients with atrial fibrillation.

Stem Cell-Derived Neurons Provide Clues Into Parkinson Disease

After transplanting hESC-derived midbrain dopamine into the striatum of a PD model mouse, researchers found extensive graft integration with host circuitry.

Alcohol-Induced Loss of Consciousness Associated with Dementia

Examining the risk of future dementia associated with overall alcohol consumption andalcohol-induced loss of consciousness amongst current drinkers.

COVID-19 Mortality Higher in Patients With Parkinson Disease

COVID-19-related case fatality rates are higher for patients with Parkinson disease, independent of age, sex, and race.

Kynmobi Now Available to Treat Off Episodes in Parkinson Disease

Apomorphine is believed to treat off episodes associated with PD through stimulation of postsynaptic dopamine D2-type receptors within the caudate-putamen in the brain.

Literature Review Explores Potential Neuroprotective Effects of Resveratrol

The eligibility criteria of the studies include: a maximum of 10 years having passed from the study publication, geographical diversity of the studies performed, and results pertaining both to animal models of AD, and to humans.

Pimavanserin Reduces Delusions and Relapse Risk in Dementia-Related Psychosis

Analysis of the HARMONY trial was conducted to evaluate the prevention of relapse in patients with dementia-related psychosis who have been treated with pimavanserin.

Ongentys Now Available as Add-On Treatment for Parkinson Disease

Ongentys is an oral, selective and reversible inhibitor of catechol-O-methyltransferase.

Individuals With a High Genetic Risk for Alzheimer’s Disease Have Altered Sleep Patterns

Is there a causal relationship between depressive disorders and late-life neurodegenerative diseases? Or, is their co-occurrence due to confounding or common risk factors, such as aging?