Funding Infusion Will Help Expand A4 Alzheimer’s Treatment Trial

Tau tangles
Tau tangles
Researchers hope to better understand the relationship between amyloid and tau.

Investigators on the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4) Study — testing the beta-amyloid scavenging drug solanezumab in clinically healthy people at elevated risk for Alzheimer’s disease — now have an extra $8 million to examine additional aspects of the disease.

The funds will support additional evaluations in a subset of A4 participants and also a complementary study of 500 individuals volunteering for the drug trial but not enrolled.

Most noteworthy will be brain PET scans aimed at measuring participants’ burdens of tau protein deposits.

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