It is important to discuss family planning and pregnancy proactively in women of childbearing age who have multiple sclerosis.
A patient presents for evaluation with painful spasms of the right arm and leg.
Findings support the efficacy of mexiletine and the potential value of N-of-1 trials for assessing interventions in some chronic rare diseases.
Researchers investigated a link between fatigue and disease worsening in patients with multiple sclerosis.
Investigators observed a wide variety of movement disorders — including restless legs syndrome, tremor, and tonic spasms — associated with early demyelinating diseases.
For relapsing-remitting multiple sclerosis (MS), the risk for conversion to secondary progressive MS is lower with initial treatment with fingolimod, alemtuzumab, or natalizumab versus glatiramer acetate or interferon beta.
Investigators observed a clinically relevant slowing of neuronal activity in patients with MS in the parietotemporal cortical areas and the thalamus significantly associated with cognitive impairment.
Researchers evaluated patients with MS to determine whether their unique problems with their sense of smell could be due to inflammatory activity or neurodegeneration.
Cognitive reserve may attenuate the impact of MS on cognitive function in some patients.
Investigators observed that monoclonal antibody ocrelizumab may reduce the risk for upper extremity disability progression in patients with primary progressive multiple sclerosis.