Neuromuscular Disorders

Latest News

New Gene Variants Identified That May Raise Risk for ALS

Variants in TP73 are associated with risk for amyotrophic lateral sclerosis (ALS), according to a study published online.

Apitegromab Fast Tracked for Spinal Muscular Atrophy

Apitegromab is a selective inhibitor of the inactive form of myostatin to block its activation in the muscle.

Accelerated Neuromuscular Aging: Effect of Type 1 Diabetes on Muscle Function and Morphology

A team of investigators from McMaster University assessed the effect of aging on skeletal muscle function in individuals with and without type 1 diabetes.

AChR Ab Levels Predict 1-Year Immunosuppressive Therapy Success in Myasthenia Gravis

A team of investigators evaluated the relationship between changes in AChR Ab levels induced by immunosuppressive treatment and myasthenia gravis prognosis at 1-year following treatment in patients with the disease.

Efgartigimod Well Tolerated and Effective for Myasthenia Gravis

Efgartigimod may be an effective and well-tolerated treatment option for patients with myasthenia gravis.

Gene Therapy Makes Strides for Infants With Spinal Muscular Atrophy

During the AAN 2021 Virtual Annual Meeting, investigators presented their findings on the safety and efficacy of onasemnogene abeparvovec (formerly AVXS-101) in presymptomatic SMA patients with 3 copies of the survival motor neuron 2 gene.

Immune Checkpoint Inhibitors Increase Risk of Neurologic Toxicities

Investigators evaluated the characteristics and risk factors for neurologic adverse events associated with immune checkpoint inhibitors.

Tacrolimus Appears Safe, Effective for Drug-Naïve Myasthenia Gravis

Investigators assessed the safety and efficacy of tacrolimus monotherapy as an initial approach for patients with drug-naïve myasthenia gravis.

Heterogeneous Movement Disorders in Patients With C9orf72 Hexanucleotide Expansions

In this retrospective review, study researchers sought to assess the presentation of movement disorders in carriers of C9orf72 hexanucleotide repeat expansions.

The Effects of ICD Coding Transition on Neurologic Diagnoses

The transition from the International Classification of Disease (ICD)-9 to ICD-10 coding system may impact estimates of neurologic disease prevalence.