Pain

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Opioid Use Not Uncommon Among Individuals With Migraine

Approximately one-third of patients with migraine reported using opioids to treat their symptoms, a practice that contrasts with current guidelines.

Mechanical Punctate Pain Threshold Linked to Migraine Headache Frequency

Mechanical pain thresholds may be used to predict the next headache attack in patients with migraine.

Positive Outcomes Reported With Novel Intranasal Dihydroergotamine for Migraine

Positive results were announced from the phase 3 STOP-301 study evaluating INP104 (intranasal dihydroergotamine mesylate; Impel NeuroPharma) for the treatment of acute migraine in adults.

Changes in Brain Function, Amygdalar Connectivity Drive Preventative Effect of CBT on Migraine

The investigators observed greater brain activations in the frontal regions associated with cognitive regulation of pain after CBT.

Methods for Injecting OnabotulinumtoxinA for Migraine Prevention Vary Between Clinicians

Researchers explored alterations in PREEMPT protocol and the explanations for them using an anonymous questionnaire to headache clinicians.

The Effects of Puberty and Menstrual Cycle on Migraine in Girls

Migraine attacks were more frequent in post-pubertal compared to pre-pubertal girls, with no observed difference in headache characteristics between the groups.

Combination Interventions Needed to Tackle Excess Mortality From Extramedical Opioids

Excess mortality occurred as the result of a number of causes, including overdose, injuries, and both infectious and noncommunicable diseases.

Study Characterizes Treatment and Prognostic Factors Associated With MS Related Trigeminal Neuralgia

Researchers sought to collect information on the characteristics of MS-related TN and on the frequency and type of medical/surgical treatments.

Chronic Pain May Increase Risk for Major Adverse Cardiac and Cerebrovascular Events

In addition to increased medical costs, chronic pain may result in long term consequences, including impaired activities of daily living, cognitive decline and depression.

Evidence Supporting Use of Compounded Topical Pain Creams Limited

Due to a lack of evidence on the safety of the ingredients used in topical pain cream, caution should be exercised when prescribing these preparations.