Pain

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Researchers Look to Building Better Prediction Model for Episodic Migraine Attacks

During the study, participants completed a survey every evening pertaining to migraine occurrence and possible migraine predictors on an iPhone specific application.

Spinal Cord Stimulation May Ease Diabetic Nerve Pain

Low-frequency spinal cord stimulation (SCS) may be effective for treating painful diabetic neuropathy (DN).

NDA Submitted for Novel Intranasal DHE for Migraine

INP104 uses proprietary technology to deliver a lower dose (1.45mg) of dihydroergotamine mesylate (DHE) to the upper nasal space.

The Role of Renin-Angiotensin System in the Pathophysiology of Migraine

While it does not influence migraine severity, the renin-angiotensin system (RAS) has an important role in the pathophysiology of migraine.

Ventral Posterior Nucleus Role in Neuropathic Pain, Neuromyelitis Optica Spectrum Disorders

Thalamic ventral posterior nucleus volume is associated with neuropathic pain intensity in patients with neuromyelitis optica spectrum disorders.

Occipital Nerve Stimulation Produces Lasting Improvements in Refractory Chronic Cluster Headache

Occipital nerve stimulation has been proposed to treat refractory chronic cluster headache but this study aimed to evaluate ONS long-term efficacy in rCCH.

Erenumab Bests Topiramate in Head-to-Head Migraine Prevention Study

The HER-MES study included 777 adult patients suffering from at least 4 migraine days/month and who were naïve to, not suitable for, or had previously failed up to 3 prophylactic treatments.

Pain Is a Prodromal Symptom, Correlate Rather Than Direct Cause of Dementia

In patients with dementia, pain is a correlate or prodromal symptom rather than a direct cause of dementia.

Chronic Migraine: Fewer Monthly Migraine Days With Eptinezumab Infusion

This phase 3, randomized, double-blind, placebo-controlled study assessed the efficacy and safety of IV infusion of eptinezumab to prevent migraine in adults with chronic migraine.

The Comprehensive Benefit of OnabotulinumtoxinA in Adults With Migraine

This post hoc analysis assessed the effect of onabotulinumtoxinA on clinically meaningful changes in headache severity, headache-related impact, and QOL in adults with chronic migraine.