Pain

Latest News

Significant Reduction in Monthly Migraine Days Observed With Rimegepant in Prevention Trial

Biohaven announced positive topline results from a pivotal phase 2/3 study evaluating rimegepant for the preventive treatment of episodic and chronic migraine in adults.

Increasing Headache Day Frequency and Intensity Increases Risk of Additional Health Concerns

The presence of migraine and increasing headache pain intensity are associated with higher rates of anxiety, depression, inflammation, and sleep conditions, among other disorders.

Pain in IBD Associated With Cognitive and Behavioral Factors

Emotions, cognitions, and behaviors are significantly associated with pain severity and pain-related interference in IBD, including pain-specific cognitions and behaviors.

Neuroimaging Used to Identify Ethnic Differences in Pain Response

Researchers find that racial differences in pain may be rooted in life experience, rather than intrinsic biology.

Rimegepant Orally Disintegrating Tablet Now Available for Acute Treatment of Migraine

Biohaven announced that rimegepant is now available for the acute treatment of migraine with or without aura in adults.

People With Migraine Often Present With Metacognitive Dysfunctions

Compared with people without migraine, people with migraine and migraine with medication overuse headache often have deficits in metacognition.

Differences in Adverse Events in Phase 2 and Phase 3 Studies: The Case of Lasmiditan

Phase 2 clinical trials investigating lasmiditan reported higher incidence and severity of TEAEs, compared with the phase 3 studies.

Galcanezumab Is Relatively Safe for Up to 1 Year in Patients With Episodic and Chronic Migraine

Treatment with humanized monoclonal antibody galcanezumab for up to 1 year was safe and tolerable for episodic and chronic migraine prophylaxis.

Computer-Adaptive Tests Offers Feasible Assessment of Patient-Reported Outcomes in Low Back Pain

The Patient-Reported Outcomes Measurement Information System (PROMIS) assessing physical function and pain interference with computer adaptive tests offers a streamlined, effective approach for measuring self-reported outcomes in patients with chronic low back pain.

Vitamin D Status May Affect Spinal Degenerative Disease, Back Pain in Older Women

Severe vitamin D deficiency was linked to lumbar degenerative disease and low back pain in postmenopausal women.