Positive data from phase 2 study of Spinraza for preventing or delaying the need for respiratory intervention or death in infants with genetically diagnosed and presymptomatic spinal muscular atrophy.
Late chronotype and daytime sleepiness are associated with unhealthy life habits, including consumption of alcohol and caffeinated beverages and smoking high school students.
In a clinical practice guideline, updated recommendations are presented for the evaluation and management of attention-deficit/hyperactivity disorder (ADHD) in children.
Maternal paracetamol use during 18 to 32 weeks of gestation is associated with a higher risk for attention problems and hyperactivity in children 42 to 47 months of age.
Daily vamorolone treatment for Duchenne muscular dystrophy suggested efficacy at doses of 2.0 and 6.0 mg/kg/d in an exploratory 24-week open-label study.
In pediatric patients with a first attack of acquired demyelinating syndrome, there exists a positive association between CSF and serum neurofilament light chain.
Anemia diagnosed during the first 30 weeks of pregnancy is associated with an increased risk for autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), and intellectual disability.
In patients with type 2 spinal muscular atrophy (SMA), the severity of functional impairment at baseline can assist in predicting the magnitude of changes over time, as well as the onset of scoliosis and the need for noninvasive ventilation.
Older age, brainstem syndrome, and polyfocal-specific magnetic resonance imaging presentation at onset are predictive of relapse risk in children with demyelinating diseases of the central nervous system.
