Folic acid is known to be beneficial in pregnancy, however, the effects of high dosages of folic acid supplements has not been thoroughly explored. 

Jesús Vioque, MD, MPH, PhD, of the Consorcio de Investigación Biomédica de Epidemiología y Salud Pública in Madrid, Spain, and colleagues examined the association between the use of high dosages of FA supplements during pregnancy and child neuropsychological development after the first year of life. The main analyses were based on a sample of 2213 children with complete information on neuropsychological development and FA supplement intake during pregnancy.

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