This article describes research conducted by Annemarieke de Jonghe, MD, of the University of Amsterdam in the Netherlands, and colleagues on the effects of melatonin in elderly patients with delirium.

Many older hospital patients experience the sudden, severe confusion known as delirium due to disruption of their normal sleep-wake cycle. The researchers found that melatonin supplements did not reduce delirium in seniors who had surgery for hip fractures. They also found that the average duration of delirium was the same for both groups of patients.

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