This study explores the possible association between neurologic improvement and recanalization in stroke patients treated with intravenous tissue plasminogen activator. 

Nandakumar Nagaraja, MD, of the University of Iowa and the National Institute of Neurological Disorders and Stroke’s Stroke Diagnostics and Therapeutics section, and colleagues, hypothesized that neurologic improvement with concurrent decline in blood pressure may be a clinical sign of recanalization after intravenous tissue plasminogen activator. The researchers confirmed the association, but said results need to be confirmed in a larger cohort.

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