HealthDay News — For older adults with acute ischemic stroke, endovascular therapy seems safe and efficacious, according to a study published in the Journal of the American Geriatrics Society.

Fabrizio Sallustio, MD, from the University of Tor Vergata in Italy, and colleagues divided 219 elderly adults treated for acute ischemic stroke according to age (≥80 years, 62 adults; <80 years, 157 adults). They compared the baseline and procedural characteristics, safety outcomes, and efficacy outcomes of the 2 groups.

The researchers found that participants aged 80 years and older more often had intravenous thrombolysis (67.7 vs 52.8%; P =.04) and had shorter onset to reperfusion time (318.7±128.7 vs 282±53.5; P =.02). There were no significant between-group differences in terms of successful reperfusion (69 vs 63%; P =.4), good clinical outcome (30.6 vs 34.3%; P =.6), any intracranial hemorrhage (37 vs 37.5%; P >.99), symptomatic intracranial hemorrhage (11 vs 14%; P =.6), or mortality (40.3 vs 29.2%; P =.14). Independent predictors of 3-month functional independence were onset National Institutes of Health Stroke Scale score (odds ratio, 0.65; P =.03) and 24-hour clinical improvement (odds ratio, 141.13; P =.01) in the older group.

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“These findings suggest that endovascular treatment for stroke in selected elderly adults could be safe and effective,” the authors write.


Sallustio F, Koch G, Motta C, et al. Efficacy and safety of mechanical thrombectomy in older adults with acute ischemic stoke [published online April 19, 2017]. J Am Geriatr Soc. doi:10.1111/jgs.14909